SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 TYR B 191
ARG B 120
ASP B 160
TYR B 129
GLU B 152
 None
ACT  B 302 (-4.0A)
ZN  B 301 (-2.5A)
None
None
 1.27A 1gahA-4nt9B:
undetectable		 1gahA-4nt9B:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 VAL B 211
LEU B 208
LEU B 192
GLU B 152
GLU B 204
 None
None
None
None
ZN  B 301 (-2.7A)
 1.30A 1mmkA-4nt9B:
undetectable		 1mmkA-4nt9B:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 HIS B  79
ASN B  59
VAL B  58
ASN B  77
ALA B  55
 None
 1.40A 2iyfA-4nt9B:
undetectable		 2iyfA-4nt9B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 ASP B 160
LEU B  82
SER B 151
ILE B  74
PHE B 187
 ZN  B 301 (-2.5A)
None
ACT  B 302 (-2.6A)
None
None
 1.46A 3ko0A-4nt9B:
undetectable
3ko0B-4nt9B:
undetectable
3ko0C-4nt9B:
undetectable
3ko0D-4nt9B:
undetectable		 3ko0A-4nt9B:
16.82
3ko0B-4nt9B:
16.82
3ko0C-4nt9B:
16.82
3ko0D-4nt9B:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 LEU B  82
SER B 151
ILE B  74
PHE B 187
ASP B 160
 None
ACT  B 302 (-2.6A)
None
None
ZN  B 301 (-2.5A)
 1.49A 3ko0C-4nt9B:
undetectable
3ko0D-4nt9B:
undetectable
3ko0E-4nt9B:
undetectable
3ko0F-4nt9B:
undetectable		 3ko0C-4nt9B:
16.82
3ko0D-4nt9B:
16.82
3ko0E-4nt9B:
16.82
3ko0F-4nt9B:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU B  82
SER B 151
ILE B  74
PHE B 187
ASP B 160
 None
ACT  B 302 (-2.6A)
None
None
ZN  B 301 (-2.5A)
 1.47A 3ko0G-4nt9B:
undetectable
3ko0H-4nt9B:
undetectable
3ko0I-4nt9B:
undetectable
3ko0J-4nt9B:
undetectable		 3ko0G-4nt9B:
16.82
3ko0H-4nt9B:
16.82
3ko0I-4nt9B:
16.82
3ko0J-4nt9B:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 ASP B 160
LEU B  82
SER B 151
ILE B  74
PHE B 187
 ZN  B 301 (-2.5A)
None
ACT  B 302 (-2.6A)
None
None
 1.43A 3ko0O-4nt9B:
undetectable
3ko0P-4nt9B:
undetectable
3ko0Q-4nt9B:
undetectable
3ko0R-4nt9B:
undetectable		 3ko0O-4nt9B:
16.82
3ko0P-4nt9B:
16.82
3ko0Q-4nt9B:
16.82
3ko0R-4nt9B:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLU B 152
ALA B  76
SER B  65
ASP B  62
LEU B  82
 None
 1.44A 3ou6D-4nt9B:
undetectable		 3ou6D-4nt9B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 TYR B 191
TYR B  64
PRO B  88
TYR B  86
 None
 1.32A 3ugrA-4nt9B:
undetectable		 3ugrA-4nt9B:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 HIS B  79
ASN B  59
VAL B  58
ASN B  77
ALA B  55
 None
 1.41A 4m83A-4nt9B:
undetectable		 4m83A-4nt9B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 HIS B  79
ASN B  59
VAL B  58
ASN B  77
ALA B  55
 None
 1.46A 4m83B-4nt9B:
undetectable		 4m83B-4nt9B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 VAL B 211
ALA B 183
TYR B 229
ALA B 215
GLY B 186
 None
 1.39A 5tzoA-4nt9B:
undetectable		 5tzoA-4nt9B:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4nt9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 VAL B 211
ALA B 183
TYR B 229
ALA B 215
GLY B 186
 None
 1.35A 5tzoC-4nt9B:
undetectable		 5tzoC-4nt9B:
21.98