SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 4nte DEPH
(Chromobacterium
violaceum) 		4 / 7 GLY A  52
ARG A  56
ILE A  61
GLY A  49
 None
None
None
NA  A 303 (-4.5A)
 0.76A 11gsB-4nteA:
undetectable		 11gsB-4nteA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 GLY A 267
ALA A 279
ALA A 265
ASP A 268
ILE A 269
 FAD  A 301 ( 3.3A)
NA  A 302 (-3.5A)
None
FAD  A 301 (-2.9A)
None
 1.15A 1nt2A-4nteA:
4.6		 1nt2A-4nteA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4nte DEPH
(Chromobacterium
violaceum) 		3 / 3 SER A  14
ASP A  35
ASP A 268
 FAD  A 301 (-2.6A)
FAD  A 301 (-3.0A)
FAD  A 301 (-2.9A)
 0.70A 3iv6A-4nteA:
3.1		 3iv6A-4nteA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4nte DEPH
(Chromobacterium
violaceum) 		3 / 3 SER A  14
ASP A  35
ASP A 268
 FAD  A 301 (-2.6A)
FAD  A 301 (-3.0A)
FAD  A 301 (-2.9A)
 0.73A 3iv6C-4nteA:
3.5		 3iv6C-4nteA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4nte DEPH
(Chromobacterium
violaceum) 		4 / 8 GLY A  52
ARG A  56
ILE A  61
GLY A  49
 None
None
None
NA  A 303 (-4.5A)
 0.78A 3n9jB-4nteA:
undetectable		 3n9jB-4nteA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 9 GLN A 236
GLU A  86
LEU A 107
LEU A 109
ILE A  11
 None
None
None
None
FAD  A 301 (-4.9A)
 1.39A 3nbqA-4nteA:
undetectable		 3nbqA-4nteA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 MET A 256
LEU A 109
ALA A 110
LEU A 229
GLY A 273
 None
None
None
None
NA  A 302 (-3.5A)
 1.07A 3olsA-4nteA:
undetectable		 3olsA-4nteA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 GLY A 287
ALA A 286
GLY A 281
ILE A 280
THR A 270
 None
 1.11A 3s56A-4nteA:
undetectable		 3s56A-4nteA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4nte DEPH
(Chromobacterium
violaceum) 		4 / 5 PHE A 111
GLY A 238
THR A 260
VAL A 263
 None
 1.09A 3wrkD-4nteA:
undetectable		 3wrkD-4nteA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 MET A 256
LEU A 109
ALA A 110
LEU A 229
GLY A 273
 None
None
None
None
NA  A 302 (-3.5A)
 1.08A 4pxmA-4nteA:
undetectable		 4pxmA-4nteA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 GLY A 283
ALA A  20
PHE A 264
ALA A 290
GLN A  23
 None
 1.31A 4ryaA-4nteA:
undetectable		 4ryaA-4nteA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 11 MET A 256
LEU A 109
ALA A 110
LEU A 229
GLY A 273
 None
None
None
None
NA  A 302 (-3.5A)
 1.12A 5dxgB-4nteA:
undetectable		 5dxgB-4nteA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 9 GLN A  23
LEU A  22
LEU A  69
VAL A   8
ALA A  75
 None
 1.40A 5g44A-4nteA:
undetectable		 5g44A-4nteA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4nte DEPH
(Chromobacterium
violaceum) 		5 / 12 MET A 256
LEU A 109
ALA A 110
LEU A 229
GLY A 273
 None
None
None
None
NA  A 302 (-3.5A)
 1.09A 5gs4A-4nteA:
undetectable		 5gs4A-4nteA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4nte DEPH
(Chromobacterium
violaceum) 		4 / 5 GLY A  13
ASP A  35
ARG A  39
GLN A  68
 None
FAD  A 301 (-3.0A)
None
None
 1.19A 5zrfB-4nteA:
undetectable		 5zrfB-4nteA:
17.16