SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ntq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4ntq ECL CDII
(Enterobacter
cloacae) 		4 / 7 PHE B   2
LEU B  34
PHE B 139
SER B  51
 None
 1.19A 1wrlE-4ntqB:
undetectable		 1wrlE-4ntqB:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ntq CONTACT-DEPENDENT
INHIBITOR A
(Enterobacter
cloacae) 		4 / 6 GLY A 189
GLY A 162
GLN A 166
PHE A 193
 None
 0.85A 2qx6A-4ntqA:
undetectable
2qx6B-4ntqA:
undetectable		 2qx6A-4ntqA:
22.31
2qx6B-4ntqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 4ntq CONTACT-DEPENDENT
INHIBITOR A
ECL CDII
(Enterobacter
cloacae) 		4 / 5 ILE B  77
GLN A 181
THR B  74
LEU B  34
 None
 1.14A 6f3mD-4ntqB:
undetectable		 6f3mD-4ntqB:
14.04