SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 6 VAL A  10
VAL A  52
ILE A  62
ASN A 269
 None
 0.89A 1e06A-4nufA:
undetectable		 1e06A-4nufA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 12 LEU A1091
LEU A1098
LEU A1101
LEU A1076
LEU A1257
LEU A1259
 None
 1.42A 1errB-4nufA:
12.4		 1errB-4nufA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 9 ALA A 278
ILE A  11
VAL A  37
ILE A   4
ILE A  62
ILE A  61
 None
 1.47A 1hshB-4nufA:
undetectable		 1hshB-4nufA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 SER A1161
PHE A1159
LEU A1101
LEU A1202
LEU A1221
 None
 1.48A 1p33C-4nufA:
undetectable		 1p33C-4nufA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		3 / 3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1301 (-2.8A)
MAL  A1301 (-4.6A)
None
 1.34A 1qu2A-4nufA:
undetectable		 1qu2A-4nufA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 7 SER A 116
ILE A 237
ILE A 118
THR A 247
 None
 0.98A 1sbrB-4nufA:
undetectable		 1sbrB-4nufA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 10 LEU A1156
LEU A1103
ALA A1104
LEU A1066
VAL A1065
 None
 1.03A 2bxgB-4nufA:
2.0		 2bxgB-4nufA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 LEU A 194
THR A 195
ALA A 348
THR A 347
ILE A 350
 None
 1.17A 3a35A-4nufA:
undetectable		 3a35A-4nufA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 LEU A 194
THR A 195
ALA A 348
THR A 347
ILE A 350
 None
 1.18A 3a35B-4nufA:
undetectable		 3a35B-4nufA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 LEU A 194
THR A 195
ALA A 348
THR A 347
ILE A 350
 None
 1.20A 3a3bA-4nufA:
undetectable		 3a3bA-4nufA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 7 VAL A 112
GLY A 302
PRO A 231
LYS A 307
 None
 0.74A 3bjwC-4nufA:
undetectable		 3bjwC-4nufA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 VAL A 345
GLY A 189
ALA A 190
LEU A 194
LEU A 162
 None
 1.00A 3hs6A-4nufA:
undetectable		 3hs6A-4nufA:
21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		9 / 12 ASP A  16
LYS A  17
GLU A  46
GLU A  47
ALA A  65
ASP A  67
ARG A  68
GLU A 113
TRP A 232
 MAL  A1301 (-3.1A)
MAL  A1301 (-3.1A)
MAL  A1301 ( 3.9A)
None
MAL  A1301 (-3.3A)
MAL  A1301 (-2.9A)
MAL  A1301 (-3.8A)
MAL  A1301 (-2.8A)
MAL  A1301 (-4.6A)
 0.96A 3jyrA-4nufA:
55.4		 3jyrA-4nufA:
58.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 7 ASN A  14
TRP A  64
GLU A 155
TYR A 157
MET A 332
TRP A 342
 MAL  A1301 (-4.0A)
MAL  A1301 (-4.5A)
MAL  A1301 (-3.2A)
MAL  A1301 (-4.0A)
MAL  A1301 ( 4.2A)
MAL  A1301 (-3.6A)
 0.30A 3jyrA-4nufA:
55.4		 3jyrA-4nufA:
58.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 12 VAL A 198
LEU A 162
GLY A 189
ALA A 190
LEU A 363
 None
 1.03A 3n8yB-4nufA:
undetectable		 3n8yB-4nufA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.50A 3w9tA-4nufA:
undetectable		 3w9tA-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.49A 3w9tB-4nufA:
undetectable		 3w9tB-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.49A 3w9tC-4nufA:
undetectable		 3w9tC-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.49A 3w9tD-4nufA:
undetectable		 3w9tD-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.49A 3w9tE-4nufA:
undetectable		 3w9tE-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 5 VAL A  25
GLY A  26
TYR A 285
ASP A  32
 None
 1.49A 3w9tG-4nufA:
undetectable		 3w9tG-4nufA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 8 PHE A1240
ALA A1067
LEU A1253
LEU A1252
 None
 0.92A 4ejgB-4nufA:
undetectable		 4ejgB-4nufA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 7 PHE A1240
ALA A1067
LEU A1253
LEU A1252
 None
 0.89A 4ejgC-4nufA:
undetectable		 4ejgC-4nufA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		4 / 7 ILE A1220
ARG A1216
ARG A1219
TRP A1151
 None
 1.49A 4f4dA-4nufA:
undetectable		 4f4dA-4nufA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 9 ALA A 266
ALA A 107
LEU A 105
LEU A 264
VAL A 263
 None
 1.15A 4or0B-4nufA:
undetectable		 4or0B-4nufA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		5 / 11 ILE A 134
LEU A 141
LEU A 124
ALA A 225
LEU A 117
 None
 1.10A 4p65E-4nufA:
undetectable
4p65F-4nufA:
undetectable
4p65J-4nufA:
undetectable
4p65L-4nufA:
undetectable		 4p65E-4nufA:
3.68
4p65F-4nufA:
4.44
4p65J-4nufA:
4.44
4p65L-4nufA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		3 / 3 ARG A 346
GLN A1143
GLU A  47
 None
 0.87A 4tvtA-4nufA:
undetectable		 4tvtA-4nufA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 12 ALA A 344
ALA A 340
GLY A 168
ALA A 190
PHE A 171
VAL A 183
 None
 1.43A 5w4zA-4nufA:
undetectable		 5w4zA-4nufA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		6 / 12 ALA A 344
ALA A 340
GLY A 168
ALA A 190
PHE A 171
VAL A 183
 None
 1.45A 5w4zB-4nufA:
undetectable		 5w4zB-4nufA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT
(Escherichia
coli;
Mus
musculus) 		3 / 3 TYR A 157
ASN A 229
LEU A 115
 MAL  A1301 (-4.0A)
None
None
 0.83A 6b58A-4nufA:
2.8		 6b58A-4nufA:
21.97