SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nuh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		4 / 8 PHE A 165
LEU A 104
PHE A 128
LEU A 109
 None
 1.02A 3i45A-4nuhA:
undetectable		 3i45A-4nuhA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 10 ASP A  34
LEU A  74
LYS A  20
ILE A  23
ILE A  31
 None
 1.22A 3kz7A-4nuhA:
undetectable		 3kz7A-4nuhA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		4 / 7 PHE A 165
GLY A 181
THR A 135
PHE A 128
 None
 0.99A 3vnsA-4nuhA:
undetectable		 3vnsA-4nuhA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		3 / 3 PHE A  91
ASP A  93
ARG A   3
 None
 0.74A 4eahF-4nuhA:
undetectable		 4eahF-4nuhA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		3 / 3 PHE A  91
ASP A  93
ARG A   3
 None
 0.75A 4eahG-4nuhA:
undetectable		 4eahG-4nuhA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 12 PHE A 128
LEU A 154
LEU A 146
VAL A 122
PHE A 179
 None
 1.09A 4wnwB-4nuhA:
undetectable		 4wnwB-4nuhA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 11 ASP A  34
LEU A  74
LYS A  20
ILE A  23
ILE A  31
 None
 1.13A 5gpgA-4nuhA:
undetectable		 5gpgA-4nuhA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 12 ALA A  65
GLY A  36
GLY A  63
GLY A  54
VAL A  52
 None
 0.97A 5i73A-4nuhA:
undetectable		 5i73A-4nuhA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 12 ALA A  65
GLY A  36
GLY A  63
GLY A  54
VAL A  52
 None
 0.96A 5i75A-4nuhA:
undetectable		 5i75A-4nuhA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 11 ILE A  56
ILE A  45
VAL A  52
ILE A  17
ALA A  19
 None
 1.11A 5lg3A-4nuhA:
undetectable		 5lg3A-4nuhA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4nuh ICE-BINDING PROTEIN
(Leucosporidium) 		5 / 12 LEU A 184
SER A 160
VAL A 182
ALA A  16
GLY A 199
 None
 1.19A 5tzoB-4nuhA:
undetectable		 5tzoB-4nuhA:
23.45