SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4nuj PGT152 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 TRP B  36
ALA B  50
VAL B  48
 None
 0.98A 1bdwA-4nujB:
undetectable
1bdwB-4nujB:
undetectable		 1bdwA-4nujB:
8.04
1bdwB-4nujB:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4nuj PGT152 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 VAL B 111
ARG B  66
VAL B  18
PHE B  67
 None
 1.41A 3jx4A-4nujB:
undetectable
3jx4B-4nujB:
undetectable		 3jx4A-4nujB:
21.23
3jx4B-4nujB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4nuj PGT152 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 VAL B 111
ARG B  66
VAL B  18
PHE B  67
 None
 1.42A 5addA-4nujB:
undetectable
5addB-4nujB:
undetectable		 5addA-4nujB:
21.23
5addB-4nujB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4nuj PGT152 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 VAL B 111
ARG B  66
VAL B  18
PHE B  67
 None
 1.41A 5adeA-4nujB:
undetectable
5adeB-4nujB:
undetectable		 5adeA-4nujB:
21.23
5adeB-4nujB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4nuj PGT152 HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA B  88
THR B  87
VAL B 109
GLU B  85
 None
 0.74A 5ecmD-4nujB:
undetectable		 5ecmD-4nujB:
17.99