SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		5 / 12 GLY A  52
MET A  96
MET A 103
ILE A 135
PHE A 131
 None
 1.39A 1m2zD-4nulA:
undetectable		 1m2zD-4nulA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		5 / 12 GLY A  52
MET A  96
MET A 103
ILE A 135
PHE A 131
 None
 1.34A 1p93D-4nulA:
undetectable		 1p93D-4nulA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		4 / 5 SER A  64
GLY A   8
GLU A  65
CYH A  53
 None
FMN  A 139 ( 3.5A)
None
None
 1.13A 3aiaA-4nulA:
undetectable
3aiaB-4nulA:
2.5		 3aiaA-4nulA:
20.75
3aiaB-4nulA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		5 / 12 GLY A  52
MET A  96
MET A 103
ILE A 135
PHE A 131
 None
 1.40A 3mneA-4nulA:
undetectable		 3mneA-4nulA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		4 / 6 LYS A  21
LEU A  18
ALA A  20
THR A  32
 None
 1.05A 4ikiB-4nulA:
undetectable		 4ikiB-4nulA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		5 / 12 GLY A  52
MET A  96
MET A 103
ILE A 135
PHE A 131
 None
 1.37A 4udcA-4nulA:
undetectable		 4udcA-4nulA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		5 / 12 LEU A  51
GLY A  52
MET A  96
ILE A 135
PHE A 131
 None
 1.27A 4udcA-4nulA:
undetectable		 4udcA-4nulA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4nul FLAVODOXIN
(Clostridium
beijerinckii) 		4 / 5 LEU A  84
PHE A 131
ILE A  50
ILE A 135
 None
 1.01A 5dzk4-4nulA:
undetectable
5dzkg-4nulA:
undetectable
5dzkm-4nulA:
undetectable
5dzkn-4nulA:
undetectable		 5dzk4-4nulA:
4.55
5dzkg-4nulA:
21.33
5dzkm-4nulA:
22.66
5dzkn-4nulA:
22.66