SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 VAL A 620
LEU A 587
LEU A 627
THR A 623
THR A 626
 None
 1.27A 1dmyA-4nurA:
undetectable		 1dmyA-4nurA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 9 GLU A 307
LEU A 349
ALA A 352
LEU A 381
LEU A 318
 None
 1.27A 1hwiA-4nurA:
undetectable		 1hwiA-4nurA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 TYR A 101
HIS A 329
GLY A 261
HIS A 367
ASP A 196
 None
None
None
ZN  A 701 (-3.4A)
ZN  A 701 (-2.5A)
 1.35A 1t69A-4nurA:
undetectable		 1t69A-4nurA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 ALA A 227
LEU A 273
SER A 553
ASN A 628
VAL A 232
 None
 1.23A 1u72A-4nurA:
undetectable		 1u72A-4nurA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 VAL A 620
ILE A 646
LEU A 622
LEU A 627
MET A 659
 None
 1.14A 2a15A-4nurA:
undetectable		 2a15A-4nurA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 8 PHE A 589
LEU A 627
LEU A 655
LEU A 585
 None
 0.92A 2bfpD-4nurA:
undetectable		 2bfpD-4nurA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 ALA A 552
ALA A 268
GLY A 269
THR A 270
ASP A 555
 None
 1.12A 2f16V-4nurA:
undetectable
2f16W-4nurA:
undetectable		 2f16V-4nurA:
16.61
2f16W-4nurA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_D_AZZD1211_1
(DEOXYNUCLEOSIDE
KINASE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 10 ILE A 127
TRP A 372
VAL A 133
ARG A 141
PHE A 131
 None
 1.48A 2jj8D-4nurA:
undetectable		 2jj8D-4nurA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		3 / 3 ARG A 202
GLY A 203
SER A 267
 None
 0.49A 2xctB-4nurA:
undetectable		 2xctB-4nurA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 5 PRO A 220
ILE A 279
PRO A 276
TYR A 218
 None
 1.00A 3d9lA-4nurA:
undetectable
3d9lY-4nurA:
undetectable		 3d9lA-4nurA:
12.48
3d9lY-4nurA:
2.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		3 / 3 TYR A 246
ASP A 144
HIS A 194
 None
 0.91A 3e23A-4nurA:
undetectable		 3e23A-4nurA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 GLY A 263
GLN A 121
GLY A 429
HIS A 329
THR A 325
 None
 1.16A 3eeyB-4nurA:
undetectable		 3eeyB-4nurA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 VAL A 205
LEU A 173
TYR A 310
VAL A 185
ILE A 150
 None
 1.10A 3frqA-4nurA:
0.0		 3frqA-4nurA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 TYR A 294
GLY A 156
GLY A 153
ALA A 187
VAL A 186
 None
 0.95A 3jb2A-4nurA:
undetectable		 3jb2A-4nurA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 6 SER A 267
ARG A 202
GLY A 203
GLU A 207
 None
 1.13A 3k9fA-4nurA:
undetectable
3k9fB-4nurA:
undetectable
3k9fD-4nurA:
undetectable		 3k9fA-4nurA:
22.05
3k9fB-4nurA:
22.05
3k9fD-4nurA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_B_ACTB600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 5 HIS A 197
ALA A 321
GLU A 303
HIS A 192
 ZN  A 701 (-3.3A)
None
None
None
 1.38A 3mbgB-4nurA:
0.0
3mbgC-4nurA:
0.0		 3mbgB-4nurA:
10.74
3mbgC-4nurA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 5 GLU A 303
HIS A 192
HIS A 197
ALA A 321
 None
None
ZN  A 701 (-3.3A)
None
 1.38A 3mbgB-4nurA:
undetectable
3mbgC-4nurA:
undetectable		 3mbgB-4nurA:
10.74
3mbgC-4nurA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 8 ASN A 231
SER A 333
GLU A 303
GLU A 307
 None
 1.07A 3sg9B-4nurA:
undetectable		 3sg9B-4nurA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 4 LEU A 292
GLY A 291
GLY A 153
THR A 158
 None
 0.95A 3si7A-4nurA:
undetectable		 3si7A-4nurA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 6 HIS A 192
HIS A 367
SER A 146
ASP A 161
 None
ZN  A 701 (-3.4A)
None
None
 1.28A 4blvA-4nurA:
undetectable		 4blvA-4nurA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 6 PHE A 223
ALA A 227
ALA A 559
THR A 556
 None
 1.03A 4dtzB-4nurA:
undetectable		 4dtzB-4nurA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 VAL A 620
LEU A 655
LEU A 627
THR A 623
THR A 626
 None
 1.23A 4lu3A-4nurA:
undetectable		 4lu3A-4nurA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 5 THR A 325
THR A 327
THR A 264
ASN A 147
 None
 1.40A 4pgfB-4nurA:
undetectable		 4pgfB-4nurA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 HIS A 192
HIS A 194
ASP A 196
HIS A 197
HIS A 367
 None
None
ZN  A 701 (-2.5A)
ZN  A 701 (-3.3A)
ZN  A 701 (-3.4A)
 0.39A 5ayaA-4nurA:
15.7		 5ayaA-4nurA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		3 / 3 THR A  49
ASP A  50
ALA A  51
 None
 0.00A 5g5gB-4nurA:
undetectable		 5g5gB-4nurA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		4 / 6 VAL A 475
LYS A 478
ALA A 479
VAL A 494
 None
 1.01A 5i8fA-4nurA:
undetectable		 5i8fA-4nurA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 11 ILE A 157
ILE A 150
VAL A 185
ASP A 161
ALA A 172
 None
 0.94A 5lg3A-4nurA:
2.1		 5lg3A-4nurA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 THR A 621
LEU A 569
LEU A 605
LEU A 658
MET A 659
 None
 1.14A 5nfjC-4nurA:
undetectable		 5nfjC-4nurA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 LEU A 145
GLY A 247
PRO A 527
ALA A 260
GLU A 538
 None
 1.22A 5x6yA-4nurA:
undetectable		 5x6yA-4nurA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 LEU A 145
GLY A 247
PRO A 527
ALA A 260
GLU A 538
 None
 1.27A 5x6yC-4nurA:
undetectable		 5x6yC-4nurA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 VAL A 188
TYR A 364
THR A 325
VAL A 204
GLY A 199
 None
 1.02A 6gngB-4nurA:
undetectable		 6gngB-4nurA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 4nur PSDSA
(Pseudomonas
sp.
S9) 		5 / 12 VAL A 188
TYR A 364
THR A 325
VAL A 204
GLY A 200
 None
 1.27A 6gngB-4nurA:
undetectable		 6gngB-4nurA:
21.13