SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 11 GLY A 119
GLY A 122
ILE A  98
LEU A 125
GLY A  45
 None
 1.11A 1jg3A-4nvrA:
undetectable		 1jg3A-4nvrA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 11 GLY A 119
GLY A 122
ILE A  98
LEU A 125
GLY A  45
 None
 1.11A 1jg3B-4nvrA:
undetectable		 1jg3B-4nvrA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 LEU A 278
THR A 137
SER A 283
VAL A 113
 None
 0.93A 1tyrB-4nvrA:
undetectable		 1tyrB-4nvrA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A 223
ASP A 222
TRP A 162
HIS A 123
 None
 1.34A 2ha2A-4nvrA:
13.5		 2ha2A-4nvrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A 223
ASP A 222
TRP A 162
HIS A 123
 None
 1.37A 2ha2B-4nvrA:
13.5		 2ha2B-4nvrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 PHE A 110
LEU A 300
CYH A 135
VAL A 133
LEU A 125
 None
 1.21A 2jn3A-4nvrA:
undetectable		 2jn3A-4nvrA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 ALA A 226
TRP A 162
LEU A 165
ALA A 227
 None
 1.16A 2jstA-4nvrA:
undetectable
2jstB-4nvrA:
undetectable		 2jstA-4nvrA:
11.18
2jstB-4nvrA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 PHE A 138
GLY A 114
CYH A 244
PHE A 299
 None
 1.13A 3ko0D-4nvrA:
undetectable
3ko0E-4nvrA:
undetectable		 3ko0D-4nvrA:
14.62
3ko0E-4nvrA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 ILE A  33
VAL A  21
LEU A  27
LEU A  71
VAL A 121
 None
 1.10A 3w68B-4nvrA:
undetectable		 3w68B-4nvrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 LEU A  68
TYR A 206
GLU A 286
SER A 283
 None
 1.19A 5umwA-4nvrA:
undetectable
5umwF-4nvrA:
undetectable		 5umwA-4nvrA:
13.61
5umwF-4nvrA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 8 GLN A 247
GLY A 114
ILE A 141
GLN A 191
ASP A 116
 None
None
None
None
CL  A 402 (-3.3A)
 1.10A 5vlmH-4nvrA:
undetectable		 5vlmH-4nvrA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A 254
TYR A 291
LEU A 278
GLY A 251
GLY A 252
 None
 0.99A 5wyqB-4nvrA:
undetectable		 5wyqB-4nvrA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4nvr PUTATIVE
ACYLTRANSFERASE
(Salmonella
enterica) 		5 / 10 ILE A  67
ILE A 242
ALA A 126
LEU A 125
ALA A  95
 None
 1.50A 5zjiB-4nvrA:
undetectable		 5zjiB-4nvrA:
15.93