SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nzk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		5 / 7 TYR A 108
PHE A 367
GLY A 111
ILE A 164
GLY A 371
 None
 1.20A 11gsB-4nzkA:
undetectable		 11gsB-4nzkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 4 ILE A 316
MET A 136
VAL A 216
GLY A 322
 None
 1.18A 1e06B-4nzkA:
undetectable		 1e06B-4nzkA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 7 TYR A 203
GLU A 186
TYR A 145
TRP A 103
 None
 1.23A 3cotA-4nzkA:
undetectable		 3cotA-4nzkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		3 / 3 HIS A 194
PHE A 251
PHE A 230
 UNL  A 404 ( 3.1A)
None
None
 0.79A 3lk0D-4nzkA:
undetectable		 3lk0D-4nzkA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 TYR A 108
GLY A 111
ILE A 164
GLY A 371
 None
 0.73A 3n9jB-4nzkA:
undetectable		 3n9jB-4nzkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		3 / 3 ASN A 308
ALA A 307
LYS A 309
 None
 0.85A 3runA-4nzkA:
undetectable		 3runA-4nzkA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		5 / 12 PHE A 362
ILE A 357
GLU A 325
VAL A 131
PHE A 208
 None
 1.35A 4a97A-4nzkA:
undetectable
4a97B-4nzkA:
undetectable		 4a97A-4nzkA:
19.62
4a97B-4nzkA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 5 CYH A 209
LEU A 314
SER A 332
LEU A 361
 None
 1.27A 4n09D-4nzkA:
2.5		 4n09D-4nzkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 6 VAL A 138
LEU A 361
ALA A 204
ALA A 324
 None
 0.61A 4zf8A-4nzkA:
undetectable		 4zf8A-4nzkA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 5 THR A 226
GLU A 197
HIS A 183
LEU A 219
 None
 1.20A 5utuH-4nzkA:
2.1		 5utuH-4nzkA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 4nzk UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 LYS A 206
ALA A 205
GLY A 200
ALA A 324
 None
 0.82A 6mdqA-4nzkA:
undetectable		 6mdqA-4nzkA:
11.14