SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A  76
VAL A  78
ILE A  33
GLY A  53
 None
 0.84A 11gsA-4o0lA:
undetectable		 11gsA-4o0lA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 GLY A  35
ALA A  44
THR A 164
ILE A  33
 NDP  A 300 (-3.3A)
None
NDP  A 300 (-4.0A)
None
 0.83A 1gtnA-4o0lA:
undetectable
1gtnK-4o0lA:
undetectable		 1gtnA-4o0lA:
15.27
1gtnK-4o0lA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 GLY A  52
ALA A  47
ALA A  44
THR A  31
ILE A 111
 None
 0.90A 1gtnL-4o0lA:
undetectable
1gtnV-4o0lA:
undetectable		 1gtnL-4o0lA:
15.27
1gtnV-4o0lA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 TYR A 181
THR A 164
ALA A 186
SER A 184
GLY A 211
 NDP  A 300 (-4.8A)
NDP  A 300 (-4.0A)
None
None
NDP  A 300 (-4.9A)
 1.31A 1nbiD-4o0lA:
6.6		 1nbiD-4o0lA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 1t85A-4o0lA:
undetectable		 1t85A-4o0lA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.82A 1t87A-4o0lA:
undetectable		 1t87A-4o0lA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 ALA A  44
THR A  31
ILE A 111
GLY A  52
ALA A  47
 None
 0.84A 1utdL-4o0lA:
undetectable
1utdM-4o0lA:
undetectable		 1utdL-4o0lA:
15.27
1utdM-4o0lA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 ALA A  44
THR A  31
ILE A 111
GLY A  52
ALA A  47
 None
 0.86A 1utdO-4o0lA:
undetectable
1utdP-4o0lA:
undetectable		 1utdO-4o0lA:
15.27
1utdP-4o0lA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 11 ALA A  44
THR A  31
ILE A 111
GLY A  52
ALA A  47
 None
 0.88A 1utdP-4o0lA:
undetectable
1utdQ-4o0lA:
undetectable		 1utdP-4o0lA:
15.27
1utdQ-4o0lA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 10 LEU A 107
PHE A 153
PHE A 161
ALA A 145
ALA A 146
 None
 1.48A 1wygA-4o0lA:
undetectable		 1wygA-4o0lA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 1yrcA-4o0lA:
undetectable		 1yrcA-4o0lA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.87A 1yrdA-4o0lA:
undetectable		 1yrdA-4o0lA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		3 / 3 THR A 134
PRO A 179
TYR A 126
 None
 0.95A 2dxrA-4o0lA:
0.5		 2dxrA-4o0lA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 6 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 2feuA-4o0lA:
undetectable		 2feuA-4o0lA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.84A 2feuB-4o0lA:
undetectable		 2feuB-4o0lA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 8 PHE A  76
VAL A  78
ILE A  33
GLY A  53
 None
 0.89A 2gssA-4o0lA:
undetectable		 2gssA-4o0lA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 8 PHE A  76
VAL A  78
ILE A  33
GLY A  53
 None
 0.89A 2gssB-4o0lA:
undetectable		 2gssB-4o0lA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 GLY A 115
GLY A  36
ILE A  33
VAL A  93
VAL A  87
 NDP  A 300 (-3.5A)
None
None
None
NDP  A 300 (-3.6A)
 0.97A 2nnkB-4o0lA:
undetectable		 2nnkB-4o0lA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 5 ILE A 162
LEU A 250
ASP A 262
ALA A 163
 None
 0.93A 2opxA-4o0lA:
5.6		 2opxA-4o0lA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.83A 2qbnA-4o0lA:
undetectable		 2qbnA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 6 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.81A 2zuhA-4o0lA:
undetectable		 2zuhA-4o0lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 6 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.84A 2zuiA-4o0lA:
undetectable		 2zuiA-4o0lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 2zwtA-4o0lA:
undetectable		 2zwtA-4o0lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 2zwuA-4o0lA:
undetectable		 2zwuA-4o0lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.84A 3fwfA-4o0lA:
undetectable		 3fwfA-4o0lA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 3fwfB-4o0lA:
undetectable		 3fwfB-4o0lA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 3fwiA-4o0lA:
undetectable		 3fwiA-4o0lA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 3fwjA-4o0lA:
undetectable		 3fwjA-4o0lA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 3l63A-4o0lA:
undetectable		 3l63A-4o0lA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 8 PHE A  76
VAL A  78
ILE A  33
GLY A  53
 None
 0.86A 3n9jA-4o0lA:
undetectable		 3n9jA-4o0lA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 TYR A 181
ILE A 208
ALA A 163
THR A 164
ILE A  40
 NDP  A 300 (-4.8A)
None
None
NDP  A 300 (-4.0A)
NDP  A 300 (-3.8A)
 1.30A 3ndiA-4o0lA:
undetectable		 3ndiA-4o0lA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 3wrhA-4o0lA:
undetectable		 3wrhA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 3wrjA-4o0lA:
undetectable		 3wrjA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.86A 3wrlA-4o0lA:
undetectable		 3wrlA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.87A 3wrlE-4o0lA:
undetectable		 3wrlE-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 3wrmA-4o0lA:
undetectable		 3wrmA-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.85A 3wrmF-4o0lA:
undetectable		 3wrmF-4o0lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 ALA A 114
GLY A  39
GLY A  36
ILE A  33
 NDP  A 300 (-3.7A)
NDP  A 300 (-3.7A)
None
None
 0.68A 4eatA-4o0lA:
3.2		 4eatA-4o0lA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 SER A 166
GLN A 178
TYR A 181
MET A 217
 NDP  A 300 (-3.5A)
None
NDP  A 300 (-4.8A)
NDP  A 300 (-3.7A)
 0.91A 4hxyB-4o0lA:
19.9		 4hxyB-4o0lA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 8 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.79A 4l4aA-4o0lA:
undetectable		 4l4aA-4o0lA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.88A 4l4gA-4o0lA:
undetectable		 4l4gA-4o0lA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 5 SER A  69
ARG A  60
THR A  88
GLU A  86
 None
NDP  A 300 (-3.4A)
NDP  A 300 ( 4.0A)
NDP  A 300 (-3.0A)
 1.21A 5btiA-4o0lA:
undetectable
5btiB-4o0lA:
2.8		 5btiA-4o0lA:
20.16
5btiB-4o0lA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		5 / 12 ALA A  56
LEU A  58
GLY A 260
THR A 258
LEU A 250
 None
 0.98A 5eshA-4o0lA:
undetectable		 5eshA-4o0lA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 6 GLY A 115
ASP A 262
ILE A 265
TYR A 247
 NDP  A 300 (-3.5A)
None
None
None
 0.97A 5iwuA-4o0lA:
undetectable		 5iwuA-4o0lA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE
(Rhodotorula
mucilaginosa) 		4 / 7 PHE A 161
TYR A 110
THR A  34
VAL A 188
 None
 0.93A 5wk9A-4o0lA:
undetectable		 5wk9A-4o0lA:
19.34