SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		6 / 8 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
None
 0.28A 1ekjA-4o1jA:
23.3
1ekjB-4o1jA:
23.5		 1ekjA-4o1jA:
35.71
1ekjB-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 8 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 0.24A 1ekjA-4o1jA:
23.3
1ekjB-4o1jA:
23.5		 1ekjA-4o1jA:
35.71
1ekjB-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 8 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 1.03A 1ekjA-4o1jA:
23.3
1ekjB-4o1jA:
23.5		 1ekjA-4o1jA:
35.71
1ekjB-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 7 CYH A  45
ASP A  47
HIS A 101
GLY A 105
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
None
None
 0.21A 1ekjE-4o1jA:
23.2
1ekjF-4o1jA:
23.2		 1ekjE-4o1jA:
35.71
1ekjF-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 7 CYH A  45
ASP A  47
HIS A 101
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
None
 0.96A 1ekjE-4o1jA:
23.2
1ekjF-4o1jA:
23.2		 1ekjE-4o1jA:
35.71
1ekjF-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 8 CYH A  45
ASP A  47
GLY A 105
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
None
None
 0.16A 1ekjE-4o1jA:
23.2
1ekjF-4o1jA:
23.2		 1ekjE-4o1jA:
35.71
1ekjF-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 8 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 0.94A 1ekjG-4o1jA:
23.3
1ekjH-4o1jA:
23.4		 1ekjG-4o1jA:
35.71
1ekjH-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		6 / 8 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
None
 0.22A 1ekjG-4o1jA:
23.3
1ekjH-4o1jA:
23.4		 1ekjG-4o1jA:
35.71
1ekjH-4o1jA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 6 CYH A  45
ASP A  47
HIS A 101
CYH A 104
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
 0.21A 1ekjG-4o1jA:
23.3
1ekjH-4o1jA:
23.4		 1ekjG-4o1jA:
35.71
1ekjH-4o1jA:
35.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 6 GLU A 137
LEU A 154
LEU A 195
GLY A 196
 None
 0.90A 1n13H-4o1jA:
undetectable
1n13K-4o1jA:
undetectable		 1n13H-4o1jA:
21.74
1n13K-4o1jA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 7 LEU A 154
LEU A 195
GLY A 196
GLU A 137
 None
 0.89A 1n13G-4o1jA:
undetectable
1n13J-4o1jA:
undetectable		 1n13G-4o1jA:
13.64
1n13J-4o1jA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 CYH A  99
HIS A 101
PHE A 184
 None
ZN  A 301 (-3.4A)
None
 1.17A 3cr4X-4o1jA:
undetectable		 3cr4X-4o1jA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 CYH A  45
CYH A 104
HIS A 101
 ZN  A 301 (-2.2A)
ZN  A 301 (-2.3A)
ZN  A 301 (-3.4A)
 0.88A 3dtuB-4o1jA:
undetectable		 3dtuB-4o1jA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 CYH A  45
CYH A 104
HIS A 101
 ZN  A 301 (-2.2A)
ZN  A 301 (-2.3A)
ZN  A 301 (-3.4A)
 0.86A 3dtuD-4o1jA:
undetectable		 3dtuD-4o1jA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 12 ILE A 160
GLY A 159
VAL A 156
ILE A  43
VAL A 180
 None
 0.85A 3fpjA-4o1jA:
undetectable		 3fpjA-4o1jA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 10 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 0.28A 3ucjA-4o1jA:
25.1		 3ucjA-4o1jA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 GLN A  36
PHE A  64
TYR A  86
 None
 0.53A 3ucjB-4o1jA:
25.9		 3ucjB-4o1jA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 GLN A  36
PHE A  64
TYR A  86
 None
 0.49A 3ucjA-4o1jA:
25.1		 3ucjA-4o1jA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 10 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 105
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 0.32A 3ucjB-4o1jA:
25.9		 3ucjB-4o1jA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 10 CYH A  45
ASP A  47
HIS A 101
CYH A 104
GLY A 106
 ZN  A 301 (-2.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-2.3A)
None
 1.12A 3ucjB-4o1jA:
25.9		 3ucjB-4o1jA:
33.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 6 VAL A  88
LEU A  41
ILE A  96
ASN A 166
 None
 0.92A 4a9kA-4o1jA:
undetectable		 4a9kA-4o1jA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 4 LEU A  98
ILE A  96
GLY A 159
ILE A 169
 None
 0.88A 5dzk3-4o1jA:
undetectable
5dzkm-4o1jA:
undetectable		 5dzk3-4o1jA:
1.47
5dzkm-4o1jA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 5 ILE A  96
GLY A 159
ILE A 169
LEU A  98
 None
 0.84A 5dzkB-4o1jA:
undetectable
5dzkI-4o1jA:
undetectable
5dzkW-4o1jA:
undetectable		 5dzkB-4o1jA:
22.76
5dzkI-4o1jA:
25.47
5dzkW-4o1jA:
1.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 5 ILE A  96
GLY A 159
ILE A 169
LEU A  98
 None
 0.81A 5dzkd-4o1jA:
undetectable
5dzkk-4o1jA:
undetectable
5dzky-4o1jA:
undetectable		 5dzkd-4o1jA:
22.76
5dzkk-4o1jA:
25.47
5dzky-4o1jA:
1.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		4 / 4 ILE A  96
GLY A 159
ILE A 169
LEU A  98
 None
 0.90A 5dzkl-4o1jA:
undetectable
5dzkz-4o1jA:
undetectable		 5dzkl-4o1jA:
25.47
5dzkz-4o1jA:
1.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 12 ILE A 116
SER A  46
GLY A 105
HIS A 101
GLY A 109
 None
None
None
ZN  A 301 (-3.4A)
None
 1.01A 5l6eA-4o1jA:
undetectable		 5l6eA-4o1jA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		3 / 3 GLU A  52
ASP A  62
PRO A  38
 None
 0.60A 6berA-4o1jA:
undetectable		 6berA-4o1jA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 4o1j CARBONIC ANHYDRASE
(Sordaria
macrospora) 		5 / 12 ASN A 155
LEU A 127
GLY A  44
ILE A  84
LEU A 163
 None
 1.09A 6dwnC-4o1jA:
undetectable		 6dwnC-4o1jA:
17.86