SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4o1n SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 142
ASN A 195
MET A 166
ILE A 133
ILE A 189
 None
 1.12A 3ut5B-4o1nA:
undetectable		 3ut5B-4o1nA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4o1n SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 164
LEU A 176
ARG A 141
ILE A 114
LEU A 112
 None
 1.10A 4m6kA-4o1nA:
undetectable		 4m6kA-4o1nA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 4o1n SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 142
ASN A 195
MET A 166
ILE A 133
ILE A 189
 None
 1.04A 4o2bB-4o1nA:
undetectable		 4o2bB-4o1nA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4o1n SUPERANTIGEN-LIKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 142
ASN A 195
MET A 166
ILE A 133
ILE A 189
 None
 1.07A 5mioB-4o1nA:
undetectable		 5mioB-4o1nA:
18.64