SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 4o1r REPLICATIVE DNA
HELICASE
(Nostoc
punctiforme) 		3 / 3 GLU A 118
ALA A   3
SER A   6
 None
 0.70A 1errB-4o1rA:
undetectable		 1errB-4o1rA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4o1r REPLICATIVE DNA
HELICASE
(Nostoc
punctiforme) 		3 / 3 TRP A  81
HIS A  73
LYS A  74
 None
 1.40A 1l7xA-4o1rA:
undetectable		 1l7xA-4o1rA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 4o1r REPLICATIVE DNA
HELICASE
(Nostoc
punctiforme) 		4 / 6 LEU A   2
PHE A  75
ILE A 135
ALA A 132
 None
 1.09A 2j5mA-4o1rA:
undetectable		 2j5mA-4o1rA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4o1r REPLICATIVE DNA
HELICASE
(Nostoc
punctiforme) 		5 / 9 ALA A  69
LEU A  87
LEU A  59
ASN A 133
ILE A 108
 None
 1.20A 3wdmC-4o1rA:
undetectable		 3wdmC-4o1rA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4o1r REPLICATIVE DNA
HELICASE
(Nostoc
punctiforme) 		3 / 3 HIS A 138
ASN A 129
LEU A  33
 None
 0.68A 6f7lB-4o1rA:
undetectable		 6f7lB-4o1rA:
15.99