SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		3 / 3 ALA A  34
VAL A 129
TRP A  77
 None
 1.01A 1gmkC-4o2hA:
undetectable
1gmkD-4o2hA:
undetectable		 1gmkC-4o2hA:
10.08
1gmkD-4o2hA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		4 / 6 TRP A  75
SER A  35
ALA A 132
HIS A  32
 None
 1.20A 3aruA-4o2hA:
undetectable		 3aruA-4o2hA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		5 / 12 LEU A 116
MET A 109
THR A 112
LEU A  25
ASP A  15
 None
 0.96A 4dc3A-4o2hA:
undetectable		 4dc3A-4o2hA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		5 / 12 ALA A 102
ALA A  99
ALA A  24
GLY A  23
LEU A  25
 None
 1.03A 4oaeA-4o2hA:
undetectable		 4oaeA-4o2hA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		4 / 5 ARG A  62
LEU A  20
ASN A  96
VAL A  97
 None
 1.49A 5os7B-4o2hA:
undetectable		 5os7B-4o2hA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		4 / 6 VAL A  18
LEU A  20
LEU A  28
TYR A  70
 None
 1.07A 6f6sA-4o2hA:
undetectable
6f6sB-4o2hA:
undetectable		 6f6sA-4o2hA:
19.33
6f6sB-4o2hA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4o2h PROTEIN BCAM1869
(Burkholderia
cenocepacia) 		4 / 5 ARG A  62
LEU A  20
ASN A  96
VAL A  97
 None
 1.49A 6gmdA-4o2hA:
undetectable		 6gmdA-4o2hA:
17.71