SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o2t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4o2t UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		5 / 12 THR A  88
VAL A 151
TYR A 150
LEU A  72
VAL A 157
 None
 1.15A 3frqA-4o2tA:
undetectable		 3frqA-4o2tA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4o2t UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ARG A 154
ASP A  76
ASP A 153
 None
 0.86A 3jb2A-4o2tA:
undetectable		 3jb2A-4o2tA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4o2t UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 PHE A 186
SER A  79
GLN A  81
 None
 0.87A 3smtA-4o2tA:
undetectable		 3smtA-4o2tA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 4o2t UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		4 / 9 TYR A 184
PHE A 122
ILE A 107
MET A  96
 None
 1.30A 4jvlA-4o2tA:
undetectable		 4jvlA-4o2tA:
21.07