SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 6 ASN A  91
PHE A 139
ALA A  82
GLY A 100
 None
None
None
PAU  A 301 (-3.4A)
 1.06A 1c8lA-4o5fA:
undetectable		 1c8lA-4o5fA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 6 ASN A  91
PHE A 139
ALA A  82
GLY A 100
 None
None
None
PAU  A 301 (-3.4A)
 1.10A 1gfzA-4o5fA:
undetectable		 1gfzA-4o5fA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 9 GLU A 131
LEU A 107
ALA A 110
HIS A 244
LEU A 247
 None
None
None
GOL  A 307 (-3.9A)
None
 1.30A 1mj2C-4o5fA:
undetectable		 1mj2C-4o5fA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 11 GLU A 131
LEU A 107
ALA A 110
HIS A 244
LEU A 247
 None
None
None
GOL  A 307 (-3.9A)
None
 1.31A 1mjlA-4o5fA:
undetectable
1mjlB-4o5fA:
undetectable		 1mjlA-4o5fA:
16.13
1mjlB-4o5fA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 9 GLU A 131
LEU A 107
ALA A 110
HIS A 244
LEU A 247
 None
None
None
GOL  A 307 (-3.9A)
None
 1.32A 1mjoA-4o5fA:
undetectable		 1mjoA-4o5fA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 9 GLU A 131
LEU A 107
ALA A 110
HIS A 244
LEU A 247
 None
None
None
GOL  A 307 (-3.9A)
None
 1.31A 1mjoB-4o5fA:
undetectable		 1mjoB-4o5fA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 9 GLU A 131
LEU A 107
ALA A 110
HIS A 244
LEU A 247
 None
None
None
GOL  A 307 (-3.9A)
None
 1.31A 1mjoC-4o5fA:
undetectable		 1mjoC-4o5fA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 10 GLN A 200
HIS A 183
LEU A 199
LEU A 237
THR A 238
 None
 1.19A 1rj6B-4o5fA:
undetectable		 1rj6B-4o5fA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 7 ALA A  60
ILE A  15
ASN A  54
ILE A  52
 None
 0.96A 1yc5A-4o5fA:
undetectable		 1yc5A-4o5fA:
20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		8 / 11 ASN A  12
VAL A  55
TYR A  93
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.65A 2f9wA-4o5fA:
14.3
2f9wB-4o5fA:
25.6		 2f9wA-4o5fA:
32.09
2f9wB-4o5fA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		6 / 8 TYR A  93
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 (-4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.50A 2f9wA-4o5fA:
14.3
2f9wB-4o5fA:
25.6		 2f9wA-4o5fA:
32.09
2f9wB-4o5fA:
32.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		3 / 3 SER A 154
THR A 128
GLN A 202
 CL  A 305 (-4.9A)
None
None
 0.85A 2fk8A-4o5fA:
undetectable		 2fk8A-4o5fA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 5 ALA A  60
ILE A  15
ASN A  54
ILE A  52
 None
 0.96A 2h4jA-4o5fA:
undetectable		 2h4jA-4o5fA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 5 ASN A  91
PHE A 139
ALA A  82
GLY A 100
 None
None
None
PAU  A 301 (-3.4A)
 1.06A 3bcrA-4o5fA:
undetectable		 3bcrA-4o5fA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		6 / 10 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
 0.35A 3bexA-4o5fA:
17.1
3bexB-4o5fA:
26.2		 3bexA-4o5fA:
24.82
3bexB-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		6 / 9 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
 0.36A 3bexA-4o5fA:
17.1
3bexB-4o5fA:
26.2		 3bexA-4o5fA:
24.82
3bexB-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.35A 3bexC-4o5fA:
26.1
3bexD-4o5fA:
26.1		 3bexC-4o5fA:
24.82
3bexD-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 10 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.34A 3bexC-4o5fA:
26.1
3bexD-4o5fA:
26.1		 3bexC-4o5fA:
24.82
3bexD-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 10 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.34A 3bexE-4o5fA:
17.7
3bexF-4o5fA:
26.3		 3bexE-4o5fA:
24.82
3bexF-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.34A 3bexE-4o5fA:
17.7
3bexF-4o5fA:
26.3		 3bexE-4o5fA:
24.82
3bexF-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.42A 3bf1A-4o5fA:
18.3
3bf1B-4o5fA:
17.6		 3bf1A-4o5fA:
24.82
3bf1B-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 12 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.46A 3bf1A-4o5fA:
18.3
3bf1B-4o5fA:
17.6		 3bf1A-4o5fA:
24.82
3bf1B-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.35A 3bf1C-4o5fA:
17.7
3bf1D-4o5fA:
26.1		 3bf1C-4o5fA:
24.82
3bf1D-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.37A 3bf1C-4o5fA:
17.7
3bf1D-4o5fA:
26.1		 3bf1C-4o5fA:
24.82
3bf1D-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.32A 3bf1E-4o5fA:
17.7
3bf1F-4o5fA:
5.6		 3bf1E-4o5fA:
24.82
3bf1F-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		7 / 11 ASN A  12
VAL A  55
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.34A 3bf1E-4o5fA:
17.7
3bf1F-4o5fA:
5.6		 3bf1E-4o5fA:
24.82
3bf1F-4o5fA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 12 ARG A 138
GLY A 137
GLY A 141
GLY A  92
ALA A 132
 None
 1.05A 3kkzB-4o5fA:
undetectable		 3kkzB-4o5fA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 7 LEU A 213
ARG A 134
THR A 140
ALA A 132
 None
CL  A 304 (-4.1A)
None
None
 1.06A 3mbgA-4o5fA:
undetectable
3mbgB-4o5fA:
undetectable		 3mbgA-4o5fA:
21.74
3mbgB-4o5fA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		5 / 11 GLN A 200
HIS A 183
LEU A 199
LEU A 237
THR A 238
 None
 1.11A 4lu3A-4o5fA:
undetectable		 4lu3A-4o5fA:
20.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		9 / 12 ASN A  12
VAL A  55
TYR A  93
LEU A  99
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-4.5A)
PAU  A 301 ( 4.6A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.00A 4o5fA-4o5fA:
44.7
4o5fB-4o5fA:
36.6		 4o5fA-4o5fA:
100.00
4o5fB-4o5fA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		9 / 12 ASN A  12
VAL A  55
TYR A  93
LEU A  99
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-4.5A)
PAU  A 301 ( 4.6A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.10A 4o5fA-4o5fA:
44.7
4o5fB-4o5fA:
36.6		 4o5fA-4o5fA:
100.00
4o5fB-4o5fA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 8 ALA A 236
ALA A 232
ALA A 229
ALA A 203
 None
 0.80A 4twdF-4o5fA:
undetectable
4twdG-4o5fA:
undetectable
4twdH-4o5fA:
undetectable
4twdI-4o5fA:
undetectable
4twdJ-4o5fA:
undetectable		 4twdF-4o5fA:
20.12
4twdG-4o5fA:
20.12
4twdH-4o5fA:
20.12
4twdI-4o5fA:
20.12
4twdJ-4o5fA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		6 / 12 THR A  22
ALA A  20
ASP A  21
LEU A   7
ILE A 108
GLY A 109
 None
 1.24A 4xi3B-4o5fA:
undetectable		 4xi3B-4o5fA:
26.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		9 / 12 ASN A  12
VAL A  55
TYR A  93
LEU A  99
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-4.5A)
PAU  A 301 ( 4.6A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.13A 5b8hA-4o5fA:
36.6
5b8hB-4o5fA:
20.5		 5b8hA-4o5fA:
71.33
5b8hB-4o5fA:
71.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		9 / 12 ASN A  12
VAL A  55
TYR A  93
LEU A  99
GLY A 100
ASP A 102
ARG A 103
THR A 129
ILE A 144
 PAU  A 301 ( 4.7A)
PAU  A 301 ( 4.5A)
PAU  A 301 (-4.5A)
PAU  A 301 ( 4.6A)
PAU  A 301 (-3.4A)
PAU  A 301 (-3.0A)
PAU  A 301 (-3.9A)
PAU  A 301 ( 4.5A)
PAU  A 301 ( 4.4A)
 0.13A 5b8hA-4o5fA:
36.6
5b8hB-4o5fA:
20.5		 5b8hA-4o5fA:
71.33
5b8hB-4o5fA:
71.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		3 / 3 GLU A 214
HIS A 118
VAL A 221
 None
CL  A 304 (-4.7A)
None
 0.79A 5trqB-4o5fA:
undetectable		 5trqB-4o5fA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 6 PRO A  47
TRP A  72
ILE A  68
GLY A  49
 None
 1.09A 6gqiA-4o5fA:
undetectable		 6gqiA-4o5fA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 7 THR A 250
ARG A 243
HIS A 241
ASP A 245
 None
None
None
GOL  A 307 (-4.6A)
 1.15A 6mn4E-4o5fA:
undetectable		 6mn4E-4o5fA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4o5f TYPE III
PANTOTHENATE KINASE
(Burkholderia
thailandensis) 		4 / 7 ALA A 105
GLY A 106
LEU A 247
GLY A  23
 None
 0.76A 6nm4A-4o5fA:
undetectable		 6nm4A-4o5fA:
20.14