SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 7 THR A 211
LEU A 205
VAL A 109
ASP A 144
 None
 1.06A 2cppA-4o5jA:
undetectable		 2cppA-4o5jA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 9 ASN A 125
ILE A 131
GLY A 110
ALA A 142
THR A 130
 None
 1.32A 2dtjA-4o5jA:
undetectable
2dtjB-4o5jA:
undetectable		 2dtjA-4o5jA:
17.86
2dtjB-4o5jA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 12 ALA A 247
ILE A 251
VAL A  89
ALA A  88
ILE A 349
 None
 1.11A 2h42B-4o5jA:
undetectable		 2h42B-4o5jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 12 ALA A 255
PHE A  69
ALA A  85
VAL A 353
GLY A 357
 None
 1.15A 2ve3B-4o5jA:
undetectable		 2ve3B-4o5jA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 11 LEU A 252
PHE A  83
SER A  80
VAL A  93
LEU A  94
 None
 1.36A 3a9eB-4o5jA:
undetectable		 3a9eB-4o5jA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 4 ASN A  72
PHE A  69
SER A  68
GLN A 293
 None
 1.48A 3v5vA-4o5jA:
undetectable		 3v5vA-4o5jA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		4 / 8 LEU A 318
TYR A 336
LEU A 342
TYR A 315
 None
 1.00A 3v81A-4o5jA:
undetectable		 3v81A-4o5jA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 11 ALA A  85
ASN A 352
SER A  80
PHE A  69
VAL A 360
 None
 1.39A 4claA-4o5jA:
undetectable		 4claA-4o5jA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4o5j UNCHARACTERIZED
PROTEIN
(Helicobacter
pylori) 		5 / 12 SER A 190
ASN A 194
LEU A  94
ILE A  90
GLN A 159
 None
None
None
None
GOL  A 503 (-4.1A)
 1.27A 4kukA-4o5jA:
undetectable		 4kukA-4o5jA:
13.67