SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4o5l FAB F045-092 HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 SER H 215
HIS H 217
HIS H 218
HIS H 220
HIS H 219
 None
 1.44A 3lxeB-4o5lH:
undetectable		 3lxeB-4o5lH:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4o5l FAB F045-092 HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.79A 5ecoD-4o5lH:
undetectable		 5ecoD-4o5lH:
16.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 4o5l FAB F045-092 HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-4o5lH:
23.6		 6cjkB-4o5lH:
53.28