SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 234
GLY A 116
ILE A 135
GLY A 237
 None
 0.85A 11gsB-4o5pA:
undetectable		 11gsB-4o5pA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 GLU A 747
ILE A 601
LEU A 698
ALA A 750
VAL A 714
 None
 1.27A 1ctrA-4o5pA:
undetectable		 1ctrA-4o5pA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 367
ARG A 350
THR A 368
 None
 0.98A 1df7A-4o5pA:
undetectable		 1df7A-4o5pA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 476
LEU A 477
HIS A 336
LEU A 649
ALA A 462
 None
 1.11A 1h9zA-4o5pA:
undetectable		 1h9zA-4o5pA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 121
VAL A 169
ASP A 123
ILE A 124
 None
 0.92A 1p7rA-4o5pA:
undetectable		 1p7rA-4o5pA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 141
ASN A 145
TRP A 247
 None
 1.02A 1r15C-4o5pA:
undetectable		 1r15C-4o5pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 141
ASN A 145
TRP A 247
 None
 1.00A 1r15D-4o5pA:
undetectable		 1r15D-4o5pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 141
ASN A 145
TRP A 247
 None
 1.00A 1r15E-4o5pA:
undetectable		 1r15E-4o5pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 141
ASN A 145
TRP A 247
 None
 0.99A 1r15F-4o5pA:
undetectable		 1r15F-4o5pA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 771
LEU A 698
PRO A 675
VAL A 597
 None
 1.03A 2hrcA-4o5pA:
2.5		 2hrcA-4o5pA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 649
LEU A 652
PHE A 653
LEU A 400
LEU A 332
 None
 1.12A 2pnjA-4o5pA:
2.7		 2pnjA-4o5pA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 238
LEU A 326
ASN A 246
LEU A 275
ARG A 365
 None
 1.11A 2riwA-4o5pA:
undetectable
2riwB-4o5pA:
undetectable		 2riwA-4o5pA:
16.55
2riwB-4o5pA:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.97A 2zxwN-4o5pA:
undetectable
2zxwW-4o5pA:
undetectable		 2zxwN-4o5pA:
19.53
2zxwW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.88A 3ablN-4o5pA:
0.3
3ablW-4o5pA:
undetectable		 3ablN-4o5pA:
19.53
3ablW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.94A 3ag2N-4o5pA:
0.6
3ag2W-4o5pA:
undetectable		 3ag2N-4o5pA:
19.53
3ag2W-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.98A 3ag4N-4o5pA:
undetectable
3ag4W-4o5pA:
undetectable		 3ag4N-4o5pA:
19.53
3ag4W-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.95A 3asnN-4o5pA:
0.3
3asnW-4o5pA:
undetectable		 3asnN-4o5pA:
19.53
3asnW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 TYR A 373
LEU A 332
THR A 368
ASN A   3
 None
 0.82A 3b6hB-4o5pA:
undetectable		 3b6hB-4o5pA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 205
LEU A 201
LEU A 151
LEU A 268
MET A 227
 None
 1.24A 3d90B-4o5pA:
undetectable		 3d90B-4o5pA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 689
HIS A 686
VAL A 685
 None
 0.91A 3elzB-4o5pA:
undetectable		 3elzB-4o5pA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 233
GLY A  68
ALA A 239
LEU A  93
THR A  72
 None
 1.07A 3mteA-4o5pA:
undetectable		 3mteA-4o5pA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 291
ARG A 720
ASP A 583
 None
 1.21A 3o7wA-4o5pA:
undetectable		 3o7wA-4o5pA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 233
GLY A  68
ALA A 239
LEU A  93
THR A  72
 None
 1.06A 3p2kA-4o5pA:
undetectable		 3p2kA-4o5pA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 659
GLU A 579
THR A 677
SER A 334
 None
 1.32A 3p2kC-4o5pA:
undetectable		 3p2kC-4o5pA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 411
GLU A 414
PHE A 274
ALA A 412
 None
 0.99A 3pgyA-4o5pA:
undetectable
3pgyB-4o5pA:
undetectable		 3pgyA-4o5pA:
19.84
3pgyB-4o5pA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 159
PHE A 265
ALA A 266
ILE A 224
PHE A 110
 None
 1.35A 3qpsA-4o5pA:
undetectable		 3qpsA-4o5pA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 486
ASP A 569
ASP A 659
 None
 0.72A 3r24A-4o5pA:
undetectable		 3r24A-4o5pA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 502
PRO A 504
GLN A 507
GLU A 505
 None
 1.16A 3s3oA-4o5pA:
undetectable		 3s3oA-4o5pA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 148
GLN A 150
PHE A 244
LEU A 248
 None
 0.95A 3x2qP-4o5pA:
undetectable
3x2qW-4o5pA:
undetectable		 3x2qP-4o5pA:
13.14
3x2qW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 339
PHE A 342
PRO A 343
 None
 0.51A 3zoaB-4o5pA:
undetectable		 3zoaB-4o5pA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 139
GLY A 140
GLU A 126
ILE A 124
 None
 0.96A 4fglD-4o5pA:
undetectable		 4fglD-4o5pA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 102
ALA A 154
TYR A 157
SER A 106
GLY A 108
 None
 1.27A 4mm4B-4o5pA:
undetectable		 4mm4B-4o5pA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 102
ALA A 154
TYR A 157
SER A 106
GLY A 108
 None
 1.26A 4mm6A-4o5pA:
undetectable		 4mm6A-4o5pA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 147
GLN A 150
LEU A 164
THR A 252
ILE A 270
 None
 1.48A 4p6xA-4o5pA:
undetectable		 4p6xA-4o5pA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 147
GLN A 150
LEU A 164
THR A 252
ILE A 270
 None
 1.41A 4p6xE-4o5pA:
undetectable		 4p6xE-4o5pA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  67
GLU A 240
GLY A 237
ASN A  74
ALA A 238
 None
 1.35A 4pclB-4o5pA:
undetectable		 4pclB-4o5pA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 238
LEU A 326
ASN A 246
LEU A 275
ARG A 365
 None
 1.14A 4x30A-4o5pA:
undetectable		 4x30A-4o5pA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 248
ALA A 245
LEU A 326
LEU A  67
GLY A 237
 None
 1.02A 4xi3C-4o5pA:
undetectable		 4xi3C-4o5pA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 803
VAL A 806
LEU A 716
VAL A 707
LEU A 603
 None
 0.98A 4y0pA-4o5pA:
undetectable		 4y0pA-4o5pA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 688
THR A 608
THR A 700
VAL A 781
 None
 1.10A 4yoaA-4o5pA:
undetectable		 4yoaA-4o5pA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.89A 5b1aN-4o5pA:
undetectable
5b1aW-4o5pA:
undetectable		 5b1aN-4o5pA:
19.53
5b1aW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 241
ASN A 246
HIS A 331
THR A 280
 None
 1.06A 5db5A-4o5pA:
undetectable
5db5B-4o5pA:
undetectable		 5db5A-4o5pA:
18.63
5db5B-4o5pA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 SER A 130
PHE A  69
GLY A 237
SER A 235
ALA A 243
 None
 1.31A 5entC-4o5pA:
undetectable		 5entC-4o5pA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 7 GLY A 118
SER A 130
GLU A 126
PHE A 121
ASP A 123
 None
 1.48A 5ergB-4o5pA:
undetectable		 5ergB-4o5pA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 295
GLY A 233
ASP A 345
LEU A 275
LEU A 277
 None
 0.99A 5wwsA-4o5pA:
undetectable		 5wwsA-4o5pA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.92A 5xdxN-4o5pA:
0.5
5xdxW-4o5pA:
undetectable		 5xdxN-4o5pA:
19.53
5xdxW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 148
GLN A 150
PHE A 244
LEU A 248
 None
 0.91A 5zcoC-4o5pA:
undetectable
5zcoJ-4o5pA:
undetectable		 5zcoC-4o5pA:
13.14
5zcoJ-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.89A 5zcoA-4o5pA:
undetectable
5zcoJ-4o5pA:
undetectable		 5zcoA-4o5pA:
19.53
5zcoJ-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 148
GLN A 150
PHE A 244
LEU A 248
 None
 0.95A 5zcqC-4o5pA:
undetectable
5zcqJ-4o5pA:
undetectable		 5zcqC-4o5pA:
13.14
5zcqJ-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 148
GLN A 150
PHE A 244
LEU A 248
 None
 0.96A 5zcqP-4o5pA:
undetectable
5zcqW-4o5pA:
undetectable		 5zcqP-4o5pA:
13.14
5zcqW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 272
LEU A 326
PHE A 325
THR A 303
 None
 0.91A 5zcqN-4o5pA:
0.4
5zcqW-4o5pA:
undetectable		 5zcqN-4o5pA:
19.53
5zcqW-4o5pA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 PHE A 773
ARG A 720
ALA A 293
 None
 0.77A 6ecfB-4o5pA:
7.1		 6ecfB-4o5pA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 332
GLY A 233
VAL A  90
LEU A  93
ILE A  94
 None
 1.03A 6ectA-4o5pA:
undetectable		 6ectA-4o5pA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 379
GLN A 389
LEU A 573
PHE A 495
 None
 1.25A 6ekuA-4o5pA:
undetectable		 6ekuA-4o5pA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 684
THR A 608
ARG A 242
ARG A 305
 None
 1.20A 6ew0B-4o5pA:
undetectable		 6ew0B-4o5pA:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 684
THR A 608
ARG A 242
ARG A 305
 None
 1.20A 6ew0D-4o5pA:
undetectable		 6ew0D-4o5pA:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 684
THR A 608
ARG A 242
ARG A 305
 None
 1.20A 6ew0H-4o5pA:
undetectable		 6ew0H-4o5pA:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 4o5p UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 684
THR A 608
ARG A 242
ARG A 305
 None
 1.20A 6ew0I-4o5pA:
undetectable		 6ew0I-4o5pA:
5.90