SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQP_A_803A311_1 (ANTIGEN CD11A (P180))	4o65	PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B (Candidatus Nitrosocaldus yellowstonensis)	5 / 10	LEU A 54 VAL A 178 ILE A 176 TYR A 155 LEU A 110	None	1.18A	1cqpA-4o65A: undetectable 1cqpB-4o65A: undetectable	1cqpA-4o65A: 23.38 1cqpB-4o65A: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R30_B_SAMB501_0 (BIOTIN SYNTHASE)	4o65	PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B (Candidatus Nitrosocaldus yellowstonensis)	5 / 12	TYR A 143 GLY A 173 HIS A 158 ILE A 108 LEU A 90	None CU A 201 ( 4.5A) CU A 201 (-3.2A) None None	1.20A	1r30B-4o65A: undetectable	1r30B-4o65A: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z97_A_CAMA422_0 (CYTOCHROME P450-CAM)	4o65	PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B (Candidatus Nitrosocaldus yellowstonensis)	4 / 6	THR A 183 LEU A 73 VAL A 76 VAL A 89	None	0.96A	2z97A-4o65A: undetectable	2z97A-4o65A: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IAZ_A_AINA1202_1 (LACTOTRANSFERRIN)	4o65	PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B (Candidatus Nitrosocaldus yellowstonensis)	3 / 3	GLU A 179 GLY A 153 THR A 154	None	0.45A	3iazA-4o65A: undetectable	3iazA-4o65A: 18.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CQP_A_803A311_1","ANTIGEN CD11A (P180);ANTIGEN CD11A (P180)","4o65","PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B","Candidatus Nitrosocaldus yellowstonensis",5,"LEU A  54;VAL A 178;ILE A 176;TYR A 155;LEU A 110","None","1.18A","1cqpA-4o65A:undetectable;1cqpB-4o65A:undetectable","1cqpA-4o65A:23.38;1cqpB-4o65A:23.38"],["1R30_B_SAMB501_0","BIOTIN SYNTHASE","4o65","PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B","Candidatus Nitrosocaldus yellowstonensis",5,"TYR A 143;GLY A 173;HIS A 158;ILE A 108;LEU A  90","None; CU A 201 ( 4.5A); CU A 201 (-3.2A);None;None","1.20A","1r30B-4o65A:undetectable","1r30B-4o65A:18.46"],["2Z97_A_CAMA422_0","CYTOCHROME P450-CAM","4o65","PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B","Candidatus Nitrosocaldus yellowstonensis",4,"THR A 183;LEU A  73;VAL A  76;VAL A  89","None","0.96A","2z97A-4o65A:undetectable","2z97A-4o65A:18.69"],["3IAZ_A_AINA1202_1","LACTOTRANSFERRIN","4o65","PUTATIVE ARCHAEAL AMMONIA MONOOXYGENASE SUBUNIT B","Candidatus Nitrosocaldus yellowstonensis",3,"GLU A 179;GLY A 153;THR A 154","None","0.45A","3iazA-4o65A:undetectable","3iazA-4o65A:18.50"]]