SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o6b NON-STRUCTURAL
PROTEIN 1
(Dengue
virus) 		5 / 11 ARG A 294
THR A 262
GLU A 334
ASN A 255
ILE A 212
 None
 1.39A 1odiD-4o6bA:
undetectable		 1odiD-4o6bA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o6b NON-STRUCTURAL
PROTEIN 1
(Dengue
virus) 		5 / 11 ARG A 294
THR A 262
GLU A 334
ASN A 255
ILE A 212
 None
 1.38A 1odiE-4o6bA:
undetectable		 1odiE-4o6bA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 4o6b NON-STRUCTURAL
PROTEIN 1
(Dengue
virus) 		5 / 12 TYR A 331
HIS A 269
GLY A 328
GLY A 325
LEU A 273
 None
 1.21A 3vywD-4o6bA:
undetectable		 3vywD-4o6bA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4o6b NON-STRUCTURAL
PROTEIN 1
(Dengue
virus) 		4 / 5 TYR A 323
LEU A 321
TYR A 260
ARG A 294
 None
 1.27A 4em2A-4o6bA:
undetectable		 4em2A-4o6bA:
18.70