SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4o6d NS1
(West
Nile
virus) 		3 / 3 GLU B 270
TRP B 330
LYS B  33
 None
 1.04A 1qu2A-4o6dB:
undetectable		 1qu2A-4o6dB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4o6d NS1
(West
Nile
virus) 		3 / 3 SER B   9
GLU B 203
ASP B 276
 None
 0.78A 2zulA-4o6dB:
undetectable		 2zulA-4o6dB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4o6d NS1
(West
Nile
virus) 		3 / 3 SER B   9
GLU B 203
ASP B 276
 None
 0.79A 3dmhA-4o6dB:
undetectable		 3dmhA-4o6dB:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4o6d NS1
(West
Nile
virus) 		3 / 3 ASP B  24
LEU B 198
GLN B  66
 None
 0.77A 3g4lA-4o6dB:
undetectable		 3g4lA-4o6dB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 4o6d NS1
(West
Nile
virus) 		4 / 5 HIS B  65
SER B  59
SER B  61
VAL B  60
 None
 1.46A 4a99D-4o6dB:
undetectable		 4a99D-4o6dB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4o6d NS1
(West
Nile
virus) 		4 / 5 TYR B 323
LEU B 321
TYR B 260
ARG B 294
 None
 1.35A 4em2A-4o6dB:
undetectable		 4em2A-4o6dB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4o6d NS1
(West
Nile
virus) 		4 / 5 ASP B  24
ASN B  23
ILE B 194
VAL B 216
 None
 1.25A 4hytA-4o6dB:
undetectable		 4hytA-4o6dB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4o6d NS1
(West
Nile
virus) 		4 / 7 ILE B 308
THR B 302
VAL B 285
ASP B 278
 None
 1.21A 4iarA-4o6dB:
undetectable		 4iarA-4o6dB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 4o6d NS1
(West
Nile
virus) 		6 / 12 PHE B 277
LEU B 321
GLY B 249
LEU B 247
ALA B 215
VAL B 220
 None
 1.30A 4wnwB-4o6dB:
undetectable		 4wnwB-4o6dB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 4o6d NS1
(West
Nile
virus) 		4 / 5 LEU B 198
ASP B  24
LEU B  63
THR B 165
 None
 1.26A 4wozF-4o6dB:
undetectable
4wozH-4o6dB:
undetectable		 4wozF-4o6dB:
24.30
4wozH-4o6dB:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4o6d NS1
(West
Nile
virus) 		5 / 12 ILE B 275
TYR B 323
GLU B 219
ALA B 297
SER B 222
 None
 1.36A 5iwuA-4o6dB:
undetectable		 5iwuA-4o6dB:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4o6d NS1
(West
Nile
virus) 		3 / 3 VAL B 273
TYR B 323
GLN B 324
 None
 0.55A 5qgkA-4o6dB:
undetectable		 5qgkA-4o6dB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4o6d NS1
(West
Nile
virus) 		3 / 3 VAL B 273
TYR B 323
GLN B 324
 None
 0.54A 5qgrA-4o6dB:
undetectable		 5qgrA-4o6dB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4o6d NS1
(West
Nile
virus) 		3 / 3 VAL B 273
TYR B 323
GLN B 324
 None
 0.56A 5qgtA-4o6dB:
undetectable		 5qgtA-4o6dB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 4o6d NS1
(West
Nile
virus) 		4 / 8 TYR B 323
ASP B 276
ASP B 278
PRO B 320
 None
 0.75A 6ag0A-4o6dB:
undetectable		 6ag0A-4o6dB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 4o6d NS1
(West
Nile
virus) 		4 / 8 TYR B 323
ASP B 276
ASP B 278
PRO B 320
 None
 0.71A 6ag0C-4o6dB:
undetectable		 6ag0C-4o6dB:
14.29