SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 4o6g UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A   8
SER A   9
ILE A  16
GLU A  78
LEU A  81
 None
 1.21A 3ko0K-4o6gA:
undetectable
3ko0L-4o6gA:
undetectable
3ko0S-4o6gA:
undetectable
3ko0T-4o6gA:
undetectable		 3ko0K-4o6gA:
22.15
3ko0L-4o6gA:
22.15
3ko0S-4o6gA:
22.15
3ko0T-4o6gA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4o6g UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 144
GLY A  83
ILE A 156
GLY A  86
PHE A  85
 None
 1.39A 3ps9A-4o6gA:
undetectable		 3ps9A-4o6gA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 4o6g UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 GLN A  25
GLY A  26
THR A  34
THR A   3
 None
 0.88A 4k87A-4o6gA:
undetectable		 4k87A-4o6gA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 4o6g UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  56
ALA A  71
MET A  74
ILE A  47
 None
 0.85A 5uihA-4o6gA:
undetectable		 5uihA-4o6gA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4o6g UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ILE A  16
PHE A  85
ARG A  44
THR A  57
 None
 1.30A 5z84N-4o6gA:
undetectable
5z84W-4o6gA:
undetectable		 5z84N-4o6gA:
15.84
5z84W-4o6gA:
12.72