SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A 269
LEU A 289
LEU A 262
ALA A 260
ILE A 266
 None
None
None
None
GOL  A 504 ( 4.0A)
 1.26A 1g5yC-4o6rA:
undetectable		 1g5yC-4o6rA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 SER A 180
THR A 181
PHE A 109
GLU A  86
 None
 1.15A 1icuA-4o6rA:
undetectable
1icuB-4o6rA:
undetectable		 1icuA-4o6rA:
19.55
1icuB-4o6rA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 HIS A 290
PHE A 257
ASP A 396
ASP A 397
 None
 1.13A 1ilqA-4o6rA:
undetectable
1ilqC-4o6rA:
undetectable		 1ilqA-4o6rA:
9.91
1ilqC-4o6rA:
3.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 SER A 180
THR A 181
PHE A 109
GLU A  86
 None
 1.12A 1kqbA-4o6rA:
undetectable
1kqbB-4o6rA:
undetectable		 1kqbA-4o6rA:
19.13
1kqbB-4o6rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 SER A 180
THR A 181
PHE A 109
GLU A  86
 None
 1.16A 1kqbC-4o6rA:
undetectable
1kqbD-4o6rA:
undetectable		 1kqbC-4o6rA:
19.13
1kqbD-4o6rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 LEU A 333
ALA A 359
ALA A 352
VAL A 332
LEU A 323
 None
 1.23A 1rlbE-4o6rA:
undetectable		 1rlbE-4o6rA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 LEU A 410
PHE A 154
MET A 153
PHE A 448
ILE A 282
 None
None
NO3  A 502 ( 4.6A)
None
NO3  A 502 (-4.8A)
 1.29A 1xosA-4o6rA:
undetectable		 1xosA-4o6rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A  83
GLN A  84
SER A  87
LEU A  88
THR A 155
 None
 1.40A 2aa5A-4o6rA:
undetectable		 2aa5A-4o6rA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A  83
GLN A  84
SER A  87
LEU A  88
THR A 155
 None
 1.41A 2aa5B-4o6rA:
undetectable		 2aa5B-4o6rA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 VAL A 442
PRO A 103
THR A 105
TRP A 157
 None
 1.39A 2q6oB-4o6rA:
2.3		 2q6oB-4o6rA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 LEU A 179
MET A   1
MET A 188
 None
 0.96A 2vavF-4o6rA:
undetectable		 2vavF-4o6rA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 GLU A  63
VAL A 169
PHE A 193
LEU A  71
ARG A  70
 None
 1.31A 3a3yA-4o6rA:
2.1		 3a3yA-4o6rA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 ALA A  81
LEU A  82
GLN A   2
ILE A  34
 None
 0.65A 3cldB-4o6rA:
undetectable		 3cldB-4o6rA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 GLY A 140
TYR A 468
GLY A 219
ASN A 167
 None
 1.08A 3e9rA-4o6rA:
undetectable		 3e9rA-4o6rA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 GLY A 140
TYR A 468
GLY A 219
ASN A 167
 None
 1.05A 3e9rC-4o6rA:
undetectable		 3e9rC-4o6rA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A 200
VAL A 201
GLU A 175
ILE A  20
LEU A 179
 None
None
AMP  A 501 (-3.6A)
None
None
 1.06A 3fpjB-4o6rA:
5.4		 3fpjB-4o6rA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 GLY A 449
MET A 460
LEU A 410
ILE A 282
 None
None
None
NO3  A 502 (-4.8A)
 0.65A 3nbqB-4o6rA:
undetectable		 3nbqB-4o6rA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 GLY A 449
MET A 460
LEU A 410
ILE A 282
 None
None
None
NO3  A 502 (-4.8A)
 0.60A 3nbqC-4o6rA:
undetectable		 3nbqC-4o6rA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 222
ILE A 233
LEU A 248
GLY A 225
TYR A 408
 None
None
None
AMP  A 501 (-3.2A)
None
 1.22A 3nrrA-4o6rA:
undetectable		 3nrrA-4o6rA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 10 LEU A 298
ILE A 255
VAL A 256
GLY A 284
ILE A 273
LEU A 289
 None
 1.49A 3ogqA-4o6rA:
undetectable		 3ogqA-4o6rA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A  40
LEU A   5
LEU A  44
ASP A  47
ILE A   7
 None
 1.15A 3wdmD-4o6rA:
undetectable		 3wdmD-4o6rA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 9 LEU A 414
ALA A 403
VAL A 288
LEU A 391
ILE A 255
 None
 1.12A 3wsjA-4o6rA:
undetectable		 3wsjA-4o6rA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 PHE A 193
GLY A 166
ALA A 165
GLY A  65
LEU A  68
 None
 0.98A 4e1gA-4o6rA:
undetectable		 4e1gA-4o6rA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 TYR A 468
LEU A 171
VAL A 146
GLN A 245
 None
 0.93A 4em2A-4o6rA:
undetectable		 4em2A-4o6rA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 ARG A 441
TRP A 435
ILE A 282
ASN A 149
 None
None
NO3  A 502 (-4.8A)
None
 1.32A 4i00A-4o6rA:
undetectable		 4i00A-4o6rA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A 282
GLY A 409
GLY A 411
MET A 433
SER A 454
 NO3  A 502 (-4.8A)
None
None
None
None
 1.09A 4iv0B-4o6rA:
4.3		 4iv0B-4o6rA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 VAL A 170
ALA A  48
PHE A   6
MET A 188
VAL A 169
 None
 1.24A 4kyaD-4o6rA:
undetectable		 4kyaD-4o6rA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 VAL A 170
ALA A  48
PHE A   6
MET A 188
VAL A 169
 None
 1.23A 4kyaF-4o6rA:
undetectable		 4kyaF-4o6rA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A 282
GLY A 409
GLY A 411
MET A 433
SER A 454
 NO3  A 502 (-4.8A)
None
None
None
None
 1.08A 4mwzA-4o6rA:
4.3		 4mwzA-4o6rA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 189
GLY A 192
GLY A   9
ARG A 183
PHE A   6
 None
 1.21A 4obwD-4o6rA:
4.0		 4obwD-4o6rA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 111
ALA A 116
GLY A 113
ASN A 167
GLY A 166
 None
 1.31A 4obwD-4o6rA:
4.0		 4obwD-4o6rA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 GLY A 321
PRO A 322
GLN A 279
 None
 0.39A 4oltB-4o6rA:
undetectable		 4oltB-4o6rA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 PHE A 448
TYR A 439
GLY A 449
SER A 454
SER A 285
 None
 1.32A 4ot2A-4o6rA:
undetectable		 4ot2A-4o6rA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 GLY A 321
PRO A 322
GLN A 279
 None
 0.36A 4qwpB-4o6rA:
undetectable		 4qwpB-4o6rA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  21
THR A 207
THR A  38
ALA A  37
ALA A  14
 None
 1.49A 4u15A-4o6rA:
undetectable		 4u15A-4o6rA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  21
THR A 207
THR A  38
ALA A  37
ALA A  14
 None
 1.50A 4u15B-4o6rA:
undetectable		 4u15B-4o6rA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.47A 4w5qA-4o6rA:
3.4		 4w5qA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.44A 4w5tA-4o6rA:
3.3		 4w5tA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 PHE A 154
GLY A 457
GLU A 459
GLN A 245
PHE A 448
 None
 1.38A 4wnuC-4o6rA:
undetectable		 4wnuC-4o6rA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.46A 4z4cA-4o6rA:
3.6		 4z4cA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.46A 4z4fA-4o6rA:
3.3		 4z4fA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.48A 4z4gA-4o6rA:
3.2		 4z4gA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  16
ALA A  36
THR A  38
THR A 207
 None
 1.45A 4z4iA-4o6rA:
3.4		 4z4iA-4o6rA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 PHE A 448
TYR A 439
GLY A 449
SER A 454
SER A 285
 None
 1.34A 4zbrA-4o6rA:
undetectable		 4zbrA-4o6rA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 ALA A  48
GLY A 196
ALA A 195
GLY A   9
 None
 0.69A 4zjzA-4o6rA:
3.3		 4zjzA-4o6rA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 154
GLU A 247
PHE A 448
GLU A 382
 None
 1.21A 5h4dA-4o6rA:
3.4		 5h4dA-4o6rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 HIS A 215
VAL A 201
GLY A 209
ALA A 208
 None
None
AMP  A 501 (-3.7A)
None
 0.86A 5hwaA-4o6rA:
undetectable		 5hwaA-4o6rA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 ILE A 282
ASN A 276
THR A 224
PHE A 154
 NO3  A 502 (-4.8A)
None
None
None
 1.13A 5x23A-4o6rA:
undetectable		 5x23A-4o6rA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 4o6r ALDEHYDE
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 GLY A 411
LEU A 410
GLY A 409
ILE A 436
VAL A 451
 None
 0.94A 6mhtA-4o6rA:
3.9		 6mhtA-4o6rA:
20.52