SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		4 / 4 GLY A  82
LEU A  81
GLY A  83
ARG A  88
 None
 1.41A 1j7kA-4o7hA:
undetectable		 1j7kA-4o7hA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 GLY A 133
VAL A 106
GLU A 105
HIS A 184
ARG A 142
 None
 1.21A 1jdvE-4o7hA:
undetectable
1jdvF-4o7hA:
undetectable		 1jdvE-4o7hA:
23.66
1jdvF-4o7hA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 LEU A 141
LEU A 170
THR A 107
VAL A 106
ALA A 176
 None
 1.23A 1n5xA-4o7hA:
undetectable		 1n5xA-4o7hA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 LEU A 141
LEU A 170
THR A 107
VAL A 106
ALA A 176
 None
 1.23A 1n5xB-4o7hA:
undetectable		 1n5xB-4o7hA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		4 / 4 ALA A  12
VAL A  16
ALA A  13
HIS A   7
 None
 1.20A 1q23F-4o7hA:
undetectable		 1q23F-4o7hA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 GLY A 133
VAL A 106
GLU A 105
HIS A 184
ARG A 142
 None
 1.24A 1vhwA-4o7hA:
undetectable
1vhwD-4o7hA:
undetectable		 1vhwA-4o7hA:
21.88
1vhwD-4o7hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 GLY A 133
VAL A 106
GLU A 105
HIS A 184
ARG A 142
 None
 1.25A 1vhwC-4o7hA:
undetectable
1vhwE-4o7hA:
undetectable		 1vhwC-4o7hA:
21.88
1vhwE-4o7hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.25A 1vhwA-4o7hA:
undetectable
1vhwD-4o7hA:
undetectable		 1vhwA-4o7hA:
21.88
1vhwD-4o7hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.24A 1vhwC-4o7hA:
undetectable
1vhwE-4o7hA:
undetectable		 1vhwC-4o7hA:
21.88
1vhwE-4o7hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 10 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.25A 1vhwB-4o7hA:
undetectable
1vhwF-4o7hA:
undetectable		 1vhwB-4o7hA:
21.88
1vhwF-4o7hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 GLY A 133
VAL A 106
GLU A 105
HIS A 184
ARG A 142
 None
 1.10A 2ac7A-4o7hA:
undetectable
2ac7B-4o7hA:
undetectable		 2ac7A-4o7hA:
21.60
2ac7B-4o7hA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.10A 2ac7A-4o7hA:
undetectable
2ac7B-4o7hA:
undetectable		 2ac7A-4o7hA:
21.60
2ac7B-4o7hA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		4 / 5 LEU A  94
ASP A 163
ALA A 162
ILE A 144
 None
 1.15A 2qhfA-4o7hA:
undetectable		 2qhfA-4o7hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		4 / 5 ARG A   2
ALA A  56
ASP A  57
GLU A  55
 None
 1.34A 2xrzA-4o7hA:
undetectable		 2xrzA-4o7hA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 9 LEU A 170
ILE A 130
PRO A 180
VAL A 179
ILE A 173
 None
 1.10A 3d1yB-4o7hA:
undetectable		 3d1yB-4o7hA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.08A 3u40B-4o7hA:
undetectable
3u40C-4o7hA:
undetectable		 3u40B-4o7hA:
21.40
3u40C-4o7hA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 11 GLY A 133
VAL A 106
GLU A 105
HIS A 184
ARG A 142
 None
 1.09A 3u40D-4o7hA:
undetectable
3u40E-4o7hA:
undetectable		 3u40D-4o7hA:
21.40
3u40E-4o7hA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.12A 3u40D-4o7hA:
undetectable
3u40E-4o7hA:
undetectable		 3u40D-4o7hA:
21.40
3u40E-4o7hA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 HIS A 184
ARG A 142
GLY A 133
VAL A 106
GLU A 105
 None
 1.08A 4danA-4o7hA:
undetectable
4danB-4o7hA:
undetectable		 4danA-4o7hA:
22.47
4danB-4o7hA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 9 LEU A 170
ILE A 130
PRO A 180
VAL A 179
ILE A 173
 None
 1.11A 5kr2D-4o7hA:
undetectable		 5kr2D-4o7hA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		5 / 12 ASP A 178
GLY A 177
ALA A 176
VAL A 111
VAL A 106
 None
 1.04A 6dh0B-4o7hA:
undetectable		 6dh0B-4o7hA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 4o7h GLUTATHIONE
S-TRANSFERASE
(Rhodospirillum
rubrum) 		3 / 3 TRP A 146
ILE A 148
ASP A 149
 None
 0.87A 6i0y7-4o7hA:
undetectable		 6i0y7-4o7hA:
8.45