SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 PHE A 126
LEU A  29
ARG A 129
VAL A  44
GLY A  45
 None
 1.01A 1e7aB-4o7iA:
undetectable		 1e7aB-4o7iA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		4 / 6 VAL A 148
GLY A 147
ALA A  10
LEU A  11
 None
 0.79A 1e7bB-4o7iA:
undetectable		 1e7bB-4o7iA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 HIS A 258
PHE A 282
ALA A 235
ALA A 296
ALA A 168
 None
 1.24A 2igtC-4o7iA:
undetectable		 2igtC-4o7iA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		3 / 3 LYS A 230
ARG A 224
VAL A 223
 PO4  A 402 (-2.8A)
None
None
 0.99A 2r2vC-4o7iA:
undetectable
2r2vD-4o7iA:
undetectable		 2r2vC-4o7iA:
9.77
2r2vD-4o7iA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 ILE A 294
PHE A 282
LEU A 136
GLU A  70
GLU A  69
 None
None
None
None
MG  A 401 (-2.7A)
 1.08A 3aocC-4o7iA:
undetectable		 3aocC-4o7iA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		4 / 7 ASP A 226
GLN A 131
TYR A 132
GLN A 228
 PO4  A 402 (-4.8A)
None
None
None
 1.04A 3l2vA-4o7iA:
undetectable		 3l2vA-4o7iA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 LEU A 117
CYH A  18
THR A  21
THR A  22
ILE A 159
 None
 1.25A 3sp9A-4o7iA:
undetectable		 3sp9A-4o7iA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 LEU A 136
VAL A  14
CYH A  18
THR A  21
THR A  22
 None
 0.89A 3sp9B-4o7iA:
undetectable		 3sp9B-4o7iA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 12 LEU A 136
LEU A 288
LEU A 263
GLY A 261
ILE A 144
 None
 1.02A 3uwlD-4o7iA:
undetectable		 3uwlD-4o7iA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		4 / 8 VAL A 148
VAL A  14
ILE A  13
TRP A 115
 None
 0.86A 4jq1B-4o7iA:
undetectable		 4jq1B-4o7iA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		4 / 5 VAL A 201
ILE A 102
PRO A  41
THR A  21
 None
 1.15A 4ze1A-4o7iA:
undetectable		 4ze1A-4o7iA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eeuE-4o7iA:
undetectable
5eeuF-4o7iA:
undetectable		 5eeuE-4o7iA:
13.55
5eeuF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eevE-4o7iA:
undetectable
5eevF-4o7iA:
undetectable		 5eevE-4o7iA:
13.55
5eevF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eewE-4o7iA:
undetectable
5eewF-4o7iA:
undetectable		 5eewE-4o7iA:
13.55
5eewF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eexE-4o7iA:
undetectable
5eexF-4o7iA:
undetectable		 5eexE-4o7iA:
13.55
5eexF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eexQ-4o7iA:
undetectable
5eexR-4o7iA:
undetectable		 5eexQ-4o7iA:
13.55
5eexR-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eeyE-4o7iA:
undetectable
5eeyF-4o7iA:
undetectable		 5eeyE-4o7iA:
13.55
5eeyF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.49A 5eeyQ-4o7iA:
undetectable
5eeyR-4o7iA:
undetectable		 5eeyQ-4o7iA:
13.55
5eeyR-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eezE-4o7iA:
undetectable
5eezF-4o7iA:
undetectable		 5eezE-4o7iA:
13.55
5eezF-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5eezQ-4o7iA:
undetectable
5eezR-4o7iA:
undetectable		 5eezQ-4o7iA:
13.55
5eezR-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef0E-4o7iA:
undetectable
5ef0F-4o7iA:
undetectable		 5ef0E-4o7iA:
13.55
5ef0F-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef0Q-4o7iA:
undetectable
5ef0R-4o7iA:
undetectable		 5ef0Q-4o7iA:
13.55
5ef0R-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef1E-4o7iA:
undetectable
5ef1F-4o7iA:
undetectable		 5ef1E-4o7iA:
13.55
5ef1F-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef1Q-4o7iA:
undetectable
5ef1R-4o7iA:
undetectable		 5ef1Q-4o7iA:
13.55
5ef1R-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef2E-4o7iA:
undetectable
5ef2F-4o7iA:
undetectable		 5ef2E-4o7iA:
13.55
5ef2F-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef2Q-4o7iA:
undetectable
5ef2R-4o7iA:
undetectable		 5ef2Q-4o7iA:
13.55
5ef2R-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef3E-4o7iA:
undetectable
5ef3F-4o7iA:
undetectable		 5ef3E-4o7iA:
13.55
5ef3F-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		5 / 9 GLY A  45
HIS A  86
THR A  33
THR A  43
ILE A 120
 None
 1.48A 5ef3Q-4o7iA:
undetectable
5ef3R-4o7iA:
undetectable		 5ef3Q-4o7iA:
13.55
5ef3R-4o7iA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE
(Entamoeba
histolytica) 		4 / 7 VAL A 295
VAL A 241
PHE A 195
ILE A 212
 None
 0.77A 5yf9B-4o7iA:
undetectable		 5yf9B-4o7iA:
12.30