SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_D_SALD1300_1 (LYSR-TYPE REGULATORY PROTEIN)	4o7q	INTERFERON-INDUCIBLE PROTEIN AIM2 (Homo sapiens)	5 / 12	THR A 65 ILE A 68 GLY A 13 LEU A 14 ILE A 17	None	1.20A	2y7kD-4o7qA: undetectable	2y7kD-4o7qA: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_B_SAMB801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	4o7q	INTERFERON-INDUCIBLE PROTEIN AIM2 (Homo sapiens)	5 / 12	GLY A 13 ASP A 15 LEU A 81 LEU A 72 ASN A 73	None	1.12A	2zw9B-4o7qA: undetectable	2zw9B-4o7qA: 8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSR_A_ACTA401_0 (CASEIN KINASE II SUBUNIT ALPHA)	4o7q	INTERFERON-INDUCIBLE PROTEIN AIM2 (Homo sapiens)	4 / 5	LYS A 26 ARG A 45 LEU A 14 ASN A 44	None	1.25A	5osrA-4o7qA: undetectable	5osrA-4o7qA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OTR_A_ACTA401_0 (CASEIN KINASE II SUBUNIT ALPHA)	4o7q	INTERFERON-INDUCIBLE PROTEIN AIM2 (Homo sapiens)	4 / 5	LYS A 26 ARG A 45 LEU A 14 ASN A 44	None	1.40A	5otrA-4o7qA: undetectable	5otrA-4o7qA: 14.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y7K_D_SALD1300_1","LYSR-TYPE REGULATORY PROTEIN","4o7q","INTERFERON-INDUCIBLE PROTEIN AIM2","Homo sapiens",5,"THR A  65;ILE A  68;GLY A  13;LEU A  14;ILE A  17","None","1.20A","2y7kD-4o7qA:undetectable","2y7kD-4o7qA:17.59"],["2ZW9_B_SAMB801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","4o7q","INTERFERON-INDUCIBLE PROTEIN AIM2","Homo sapiens",5,"GLY A  13;ASP A  15;LEU A  81;LEU A  72;ASN A  73","None","1.12A","2zw9B-4o7qA:undetectable","2zw9B-4o7qA:8.63"],["5OSR_A_ACTA401_0","CASEIN KINASE II SUBUNIT ALPHA","4o7q","INTERFERON-INDUCIBLE PROTEIN AIM2","Homo sapiens",4,"LYS A  26;ARG A  45;LEU A  14;ASN A  44","None","1.25A","5osrA-4o7qA:undetectable","5osrA-4o7qA:14.93"],["5OTR_A_ACTA401_0","CASEIN KINASE II SUBUNIT ALPHA","4o7q","INTERFERON-INDUCIBLE PROTEIN AIM2","Homo sapiens",4,"LYS A  26;ARG A  45;LEU A  14;ASN A  44","None","1.40A","5otrA-4o7qA:undetectable","5otrA-4o7qA:14.93"]]