SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B60_B_RITB100_1 (GAG-POL POLYPROTEIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	GLY A 296 ILE A 145 ILE A 289 ALA A 139 ILE A 143	None	0.77A	2b60A-4o89A: undetectable	2b60A-4o89A: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B60_B_RITB100_2 (GAG-POL POLYPROTEIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 11	GLY A 296 ILE A 145 ILE A 289 ALA A 139 ILE A 143	None	0.73A	2b60B-4o89A: undetectable	2b60B-4o89A: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2001_1 (SERUM ALBUMIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 11	LEU A 132 ILE A 149 VAL A 168 GLY A 147 LEU A 103	None	1.28A	2bxeA-4o89A: undetectable	2bxeA-4o89A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2001_1 (SERUM ALBUMIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	LEU A 132 ILE A 149 VAL A 168 GLY A 147 LEU A 103	None	1.27A	2bxeB-4o89A: undetectable	2bxeB-4o89A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FN1_B_SALB503_1 (SALICYLATE SYNTHETASE, IRP9)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 11	ILE A 95 GLY A 90 HIS A 50 THR A 118 GLY A 120	None	1.37A	2fn1B-4o89A: undetectable	2fn1B-4o89A: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RKF_A_AB1A501_1 (PROTEASE RETROPEPSIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	GLY A 296 ILE A 145 ILE A 289 ALA A 139 ILE A 143	None	0.78A	2rkfA-4o89A: undetectable	2rkfA-4o89A: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VH3_A_DAHA2_1 (RANASMURFIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 9	ALA A 206 ALA A 202 SER A 234 GLY A 253 ALA A 259	None	1.39A	2vh3A-4o89A: undetectable	2vh3A-4o89A: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWC_B_SAMB501_0 (SPERMIDINE SYNTHASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	LEU A 132 HIS A 193 ILE A 163 ASP A 122 ILE A 117	None	0.96A	3bwcB-4o89A: undetectable	3bwcB-4o89A: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K9F_H_LFXH0_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 6	ARG A 154 GLY A 190 GLU A 241 GLU A 189	None	1.10A	3k9fA-4o89A: 2.2 3k9fB-4o89A: 2.3 3k9fD-4o89A: undetectable	3k9fA-4o89A: 23.31 3k9fB-4o89A: 23.31 3k9fD-4o89A: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_K_TFPK202_1 (PROTEIN S100-A4)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	LEU A 16 SER A 19 ILE A 52 LEU A 73 SER A 317	None	1.10A	3ko0K-4o89A: undetectable 3ko0L-4o89A: undetectable 3ko0S-4o89A: undetectable 3ko0T-4o89A: undetectable	3ko0K-4o89A: 15.84 3ko0L-4o89A: 15.84 3ko0S-4o89A: 15.84 3ko0T-4o89A: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N6D_B_H4BB600_1 (NITRIC OXIDE SYNTHASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 6	TRP A 171 PHE A 291 VAL A 168 PRO A 290	None	1.33A	3n6dA-4o89A: 2.8 3n6dB-4o89A: undetectable	3n6dA-4o89A: 20.93 3n6dB-4o89A: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R24_A_SAMA302_0 (2'-O-METHYL TRANSFERASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	ASN A 41 GLY A 13 PRO A 42 GLY A 43 ASP A 286	None CIT A 401 (-3.2A) None None None	1.09A	3r24A-4o89A: undetectable	3r24A-4o89A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_B_BEZB1_0 (HEME-BINDING PROTEIN HUTZ)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 6	GLN A 100 PHE A 291 PRO A 290 LEU A 288	None	1.03A	3tgvB-4o89A: undetectable	3tgvB-4o89A: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_D_BEZD1_0 (HEME-BINDING PROTEIN HUTZ)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 6	GLN A 100 PHE A 291 PRO A 290 LEU A 288	None	1.05A	3tgvD-4o89A: undetectable	3tgvD-4o89A: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_B_PXLB300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 9	GLY A 120 ASP A 122 GLY A 155 VAL A 164 HIS A 193	None	1.48A	4c5lB-4o89A: undetectable	4c5lB-4o89A: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA504_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 8	GLY A 285 LEU A 288 ILE A 289 ILE A 335	None	0.63A	4em2A-4o89A: undetectable	4em2A-4o89A: 18.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O8J_A_ADNA401_1 (RNA 3'-TERMINAL PHOSPHATE CYCLASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	11 / 12	GLN A 14 ARG A 17 LEU A 97 PRO A 127 PRO A 128 TYR A 131 ASP A 250 PHE A 283 ASP A 286 GLN A 287 HIS A 307	None CIT A 401 (-3.0A) None None None None None None None None None	0.96A	4o8jA-4o89A: 56.9	4o8jA-4o89A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O8J_A_ADNA401_1 (RNA 3'-TERMINAL PHOSPHATE CYCLASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	6 / 12	LEU A 97 GLN A 100 PRO A 127 ASP A 286 GLN A 287 HIS A 307	None	1.18A	4o8jA-4o89A: 56.9	4o8jA-4o89A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O8J_B_ADNB401_1 (RNA 3'-TERMINAL PHOSPHATE CYCLASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	11 / 12	GLN A 14 ARG A 17 LEU A 97 PRO A 127 PRO A 128 TYR A 131 ASP A 250 PHE A 283 ASP A 286 GLN A 287 HIS A 307	None CIT A 401 (-3.0A) None None None None None None None None None	1.01A	4o8jB-4o89A: 56.8	4o8jB-4o89A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O8J_B_ADNB401_1 (RNA 3'-TERMINAL PHOSPHATE CYCLASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	6 / 12	LEU A 97 GLN A 100 PRO A 127 ASP A 286 GLN A 287 HIS A 307	None	1.20A	4o8jB-4o89A: 56.8	4o8jB-4o89A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_A_IPHA101_0 (INSULIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 10	CYH A 279 LEU A 245 ALA A 139 LEU A 292 LEU A 284	None	1.17A	4p65A-4o89A: undetectable 4p65B-4o89A: undetectable 4p65F-4o89A: undetectable 4p65H-4o89A: undetectable	4p65A-4o89A: 8.28 4p65B-4o89A: 7.54 4p65F-4o89A: 7.54 4p65H-4o89A: 7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_A_IPHA101_0 (INSULIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 10	CYH A 279 LEU A 245 LEU A 177 ALA A 139 LEU A 284	None	1.20A	4p65A-4o89A: undetectable 4p65B-4o89A: undetectable 4p65F-4o89A: undetectable 4p65H-4o89A: undetectable	4p65A-4o89A: 8.28 4p65B-4o89A: 7.54 4p65F-4o89A: 7.54 4p65H-4o89A: 7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_C_IPHC101_0 (INSULIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 11	CYH A 279 LEU A 245 ALA A 139 LEU A 284 LEU A 292	None	1.12A	4p65C-4o89A: undetectable 4p65D-4o89A: undetectable 4p65J-4o89A: undetectable 4p65L-4o89A: undetectable	4p65C-4o89A: 8.28 4p65D-4o89A: 7.54 4p65J-4o89A: 7.54 4p65L-4o89A: 7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YMG_B_SAMB1001_1 (PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	3 / 3	SER A 295 GLU A 141 GLU A 241	None	0.83A	4ymgB-4o89A: undetectable	4ymgB-4o89A: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H8T_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	LEU A 284 LEU A 245 ALA A 139 ILE A 322 ILE A 299	None	1.07A	5h8tA-4o89A: undetectable	5h8tA-4o89A: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_A_SAMA306_1 (METHYLTRANSFERASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 7	LEU A 140 PHE A 291 SER A 295 ILE A 335	None	0.92A	5n5dA-4o89A: 4.0	5n5dA-4o89A: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VYH_A_FOLA409_0 (S PROTEIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 10	PRO A 258 ALA A 206 GLY A 190 ILE A 222 ALA A 202	None	1.35A	5vyhA-4o89A: undetectable	5vyhA-4o89A: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_B_RFPB502_1 (RIFAMPIN MONOOXYGENASE)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	GLY A 166 ARG A 116 THR A 121 GLY A 120 GLY A 119	None	1.11A	6brdB-4o89A: undetectable	6brdB-4o89A: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CK2_C_IPHC101_0 (INSULIN A CHAIN INSULIN B CHAIN)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	4 / 4	ILE A 95 LEU A 102 HIS A 50 ALA A 54	None	0.78A	6ck2C-4o89A: undetectable 6ck2D-4o89A: undetectable	6ck2C-4o89A: 8.28 6ck2D-4o89A: 7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRIL CHIMERA)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	LEU A 16 VAL A 20 SER A 23 THR A 24 ALA A 59	None	1.03A	6drxA-4o89A: undetectable	6drxA-4o89A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRIL CHIMERA)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 12	VAL A 20 SER A 23 THR A 24 ALA A 59 VAL A 74	None	1.43A	6drxA-4o89A: undetectable	6drxA-4o89A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NQA_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	4o89	RNA 3'-TERMINAL PHOSPHATE CYCLASE (Pyrococcus horikoshii)	5 / 10	ASP A 122 GLY A 155 GLY A 120 VAL A 129 LYS A 159	None	1.40A	6nqaK-4o89A: undetectable	6nqaK-4o89A: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2B60_B_RITB100_1","GAG-POL POLYPROTEIN;GAG-POL POLYPROTEIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"GLY A 296;ILE A 145;ILE A 289;ALA A 139;ILE A 143","None","0.77A","2b60A-4o89A:undetectable","2b60A-4o89A:16.35"],["2B60_B_RITB100_2","GAG-POL POLYPROTEIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"GLY A 296;ILE A 145;ILE A 289;ALA A 139;ILE A 143","None","0.73A","2b60B-4o89A:undetectable","2b60B-4o89A:16.35"],["2BXE_A_1FLA2001_1","SERUM ALBUMIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A 132;ILE A 149;VAL A 168;GLY A 147;LEU A 103","None","1.28A","2bxeA-4o89A:undetectable","2bxeA-4o89A:18.66"],["2BXE_B_1FLB2001_1","SERUM ALBUMIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A 132;ILE A 149;VAL A 168;GLY A 147;LEU A 103","None","1.27A","2bxeB-4o89A:undetectable","2bxeB-4o89A:18.66"],["2FN1_B_SALB503_1","SALICYLATE SYNTHETASE, IRP9","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"ILE A  95;GLY A  90;HIS A  50;THR A 118;GLY A 120","None","1.37A","2fn1B-4o89A:undetectable","2fn1B-4o89A:21.33"],["2RKF_A_AB1A501_1","PROTEASE RETROPEPSIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"GLY A 296;ILE A 145;ILE A 289;ALA A 139;ILE A 143","None","0.78A","2rkfA-4o89A:undetectable","2rkfA-4o89A:17.69"],["2VH3_A_DAHA2_1","RANASMURFIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"ALA A 206;ALA A 202;SER A 234;GLY A 253;ALA A 259","None","1.39A","2vh3A-4o89A:undetectable","2vh3A-4o89A:16.42"],["3BWC_B_SAMB501_0","SPERMIDINE SYNTHASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A 132;HIS A 193;ILE A 163;ASP A 122;ILE A 117","None","0.96A","3bwcB-4o89A:undetectable","3bwcB-4o89A:21.78"],["3K9F_H_LFXH0_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"ARG A 154;GLY A 190;GLU A 241;GLU A 189","None","1.10A","3k9fA-4o89A:2.2;3k9fB-4o89A:2.3;3k9fD-4o89A:undetectable","3k9fA-4o89A:23.31;3k9fB-4o89A:23.31;3k9fD-4o89A:23.06"],["3KO0_K_TFPK202_1","PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4;PROTEIN S100-A4","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A  16;SER A  19;ILE A  52;LEU A  73;SER A 317","None","1.10A","3ko0K-4o89A:undetectable;3ko0L-4o89A:undetectable;3ko0S-4o89A:undetectable;3ko0T-4o89A:undetectable","3ko0K-4o89A:15.84;3ko0L-4o89A:15.84;3ko0S-4o89A:15.84;3ko0T-4o89A:15.84"],["3N6D_B_H4BB600_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"TRP A 171;PHE A 291;VAL A 168;PRO A 290","None","1.33A","3n6dA-4o89A:2.8;3n6dB-4o89A:undetectable","3n6dA-4o89A:20.93;3n6dB-4o89A:20.93"],["3R24_A_SAMA302_0","2'-O-METHYL TRANSFERASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"ASN A  41;GLY A  13;PRO A  42;GLY A  43;ASP A 286","None;CIT A 401 (-3.2A);None;None;None","1.09A","3r24A-4o89A:undetectable","3r24A-4o89A:undetectable"],["3TGV_B_BEZB1_0","HEME-BINDING PROTEIN HUTZ","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"GLN A 100;PHE A 291;PRO A 290;LEU A 288","None","1.03A","3tgvB-4o89A:undetectable","3tgvB-4o89A:18.31"],["3TGV_D_BEZD1_0","HEME-BINDING PROTEIN HUTZ","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"GLN A 100;PHE A 291;PRO A 290;LEU A 288","None","1.05A","3tgvD-4o89A:undetectable","3tgvD-4o89A:18.31"],["4C5L_B_PXLB300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"GLY A 120;ASP A 122;GLY A 155;VAL A 164;HIS A 193","None","1.48A","4c5lB-4o89A:undetectable","4c5lB-4o89A:22.70"],["4EM2_A_SALA504_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"GLY A 285;LEU A 288;ILE A 289;ILE A 335","None","0.63A","4em2A-4o89A:undetectable","4em2A-4o89A:18.77"],["4O8J_A_ADNA401_1","RNA 3'-TERMINAL PHOSPHATE CYCLASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",11,"GLN A  14;ARG A  17;LEU A  97;PRO A 127;PRO A 128;TYR A 131;ASP A 250;PHE A 283;ASP A 286;GLN A 287;HIS A 307","None;CIT A 401 (-3.0A);None;None;None;None;None;None;None;None;None","0.96A","4o8jA-4o89A:56.9","4o8jA-4o89A:100.00"],["4O8J_A_ADNA401_1","RNA 3'-TERMINAL PHOSPHATE CYCLASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",6,"LEU A  97;GLN A 100;PRO A 127;ASP A 286;GLN A 287;HIS A 307","None","1.18A","4o8jA-4o89A:56.9","4o8jA-4o89A:100.00"],["4O8J_B_ADNB401_1","RNA 3'-TERMINAL PHOSPHATE CYCLASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",11,"GLN A  14;ARG A  17;LEU A  97;PRO A 127;PRO A 128;TYR A 131;ASP A 250;PHE A 283;ASP A 286;GLN A 287;HIS A 307","None;CIT A 401 (-3.0A);None;None;None;None;None;None;None;None;None","1.01A","4o8jB-4o89A:56.8","4o8jB-4o89A:100.00"],["4O8J_B_ADNB401_1","RNA 3'-TERMINAL PHOSPHATE CYCLASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",6,"LEU A  97;GLN A 100;PRO A 127;ASP A 286;GLN A 287;HIS A 307","None","1.20A","4o8jB-4o89A:56.8","4o8jB-4o89A:100.00"],["4P65_A_IPHA101_0","INSULIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"CYH A 279;LEU A 245;ALA A 139;LEU A 292;LEU A 284","None","1.17A","4p65A-4o89A:undetectable;4p65B-4o89A:undetectable;4p65F-4o89A:undetectable;4p65H-4o89A:undetectable","4p65A-4o89A:8.28;4p65B-4o89A:7.54;4p65F-4o89A:7.54;4p65H-4o89A:7.54"],["4P65_A_IPHA101_0","INSULIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"CYH A 279;LEU A 245;LEU A 177;ALA A 139;LEU A 284","None","1.20A","4p65A-4o89A:undetectable;4p65B-4o89A:undetectable;4p65F-4o89A:undetectable;4p65H-4o89A:undetectable","4p65A-4o89A:8.28;4p65B-4o89A:7.54;4p65F-4o89A:7.54;4p65H-4o89A:7.54"],["4P65_C_IPHC101_0","INSULIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"CYH A 279;LEU A 245;ALA A 139;LEU A 284;LEU A 292","None","1.12A","4p65C-4o89A:undetectable;4p65D-4o89A:undetectable;4p65J-4o89A:undetectable;4p65L-4o89A:undetectable","4p65C-4o89A:8.28;4p65D-4o89A:7.54;4p65J-4o89A:7.54;4p65L-4o89A:7.54"],["4YMG_B_SAMB1001_1","PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",3,"SER A 295;GLU A 141;GLU A 241","None","0.83A","4ymgB-4o89A:undetectable","4ymgB-4o89A:22.10"],["5H8T_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A 284;LEU A 245;ALA A 139;ILE A 322;ILE A 299","None","1.07A","5h8tA-4o89A:undetectable","5h8tA-4o89A:18.33"],["5N5D_A_SAMA306_1","METHYLTRANSFERASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"LEU A 140;PHE A 291;SER A 295;ILE A 335","None","0.92A","5n5dA-4o89A:4.0","5n5dA-4o89A:20.77"],["5VYH_A_FOLA409_0","S PROTEIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"PRO A 258;ALA A 206;GLY A 190;ILE A 222;ALA A 202","None","1.35A","5vyhA-4o89A:undetectable","5vyhA-4o89A:21.98"],["6BRD_B_RFPB502_1","RIFAMPIN MONOOXYGENASE","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"GLY A 166;ARG A 116;THR A 121;GLY A 120;GLY A 119","None","1.11A","6brdB-4o89A:undetectable","6brdB-4o89A:16.13"],["6CK2_C_IPHC101_0","INSULIN A CHAIN;INSULIN B CHAIN","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",4,"ILE A  95;LEU A 102;HIS A  50;ALA A  54","None","0.78A","6ck2C-4o89A:undetectable;6ck2D-4o89A:undetectable","6ck2C-4o89A:8.28;6ck2D-4o89A:7.21"],["6DRX_A_H8GA1201_0","5HT2B RECEPTOR, BRIL CHIMERA","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"LEU A  16;VAL A  20;SER A  23;THR A  24;ALA A  59","None","1.03A","6drxA-4o89A:undetectable","6drxA-4o89A:22.51"],["6DRX_A_H8GA1201_0","5HT2B RECEPTOR, BRIL CHIMERA","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"VAL A  20;SER A  23;THR A  24;ALA A  59;VAL A  74","None","1.43A","6drxA-4o89A:undetectable","6drxA-4o89A:22.51"],["6NQA_K_SAMK500_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","4o89","RNA 3'-TERMINAL PHOSPHATE CYCLASE","Pyrococcus horikoshii",5,"ASP A 122;GLY A 155;GLY A 120;VAL A 129;LYS A 159","None","1.40A","6nqaK-4o89A:undetectable","6nqaK-4o89A:21.43"]]