SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4o8s PUTATIVE
(Helicobacter
pylori) 		4 / 6 LEU A 112
TYR A  95
ILE A 114
GLY A  68
 None
 0.79A 2du8A-4o8sA:
undetectable		 2du8A-4o8sA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4o8s PUTATIVE
(Helicobacter
pylori) 		4 / 6 LEU A 112
TYR A  95
ILE A 114
GLY A  68
 None
 0.79A 2du8B-4o8sA:
undetectable		 2du8B-4o8sA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 4o8s PUTATIVE
(Helicobacter
pylori) 		5 / 12 GLY A  39
ARG A 154
PHE A 174
LEU A 178
VAL A  36
 None
 1.16A 2w8yA-4o8sA:
undetectable		 2w8yA-4o8sA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4o8s PUTATIVE
(Helicobacter
pylori) 		5 / 11 ALA A 167
LEU A 166
TYR A 170
ASN A  50
LEU A  49
 None
 0.91A 4wg0C-4o8sA:
undetectable
4wg0D-4o8sA:
undetectable
4wg0E-4o8sA:
undetectable		 4wg0C-4o8sA:
7.43
4wg0D-4o8sA:
7.43
4wg0E-4o8sA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4o8s PUTATIVE
(Helicobacter
pylori) 		5 / 11 ALA A 167
LEU A 166
TYR A 170
ASN A  50
LEU A  49
 None
 0.86A 4wg0E-4o8sA:
undetectable
4wg0F-4o8sA:
undetectable
4wg0G-4o8sA:
undetectable		 4wg0E-4o8sA:
7.43
4wg0F-4o8sA:
7.43
4wg0G-4o8sA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4o8s PUTATIVE
(Helicobacter
pylori) 		4 / 5 GLU A  40
THR A  41
THR A 109
HIS A  84
 None
 1.24A 5axaA-4o8sA:
undetectable		 5axaA-4o8sA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4o8s PUTATIVE
(Helicobacter
pylori) 		4 / 5 GLU A  40
THR A  41
THR A 109
HIS A  84
 None
 1.27A 5axaC-4o8sA:
undetectable		 5axaC-4o8sA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 4o8s PUTATIVE
(Helicobacter
pylori) 		3 / 3 PHE A  58
ASP A  59
LYS A  38
 None
 0.88A 6awtD-4o8sA:
undetectable		 6awtD-4o8sA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 4o8s PUTATIVE
(Helicobacter
pylori) 		4 / 4 PHE A 185
ASP A 184
LEU A 192
LYS A 187
 None
 0.92A 6awvA-4o8sA:
undetectable		 6awvA-4o8sA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4o8s PUTATIVE
(Helicobacter
pylori) 		5 / 10 ARG A  69
VAL A  70
ALA A  73
LEU A  66
LEU A 112
 None
 0.89A 6f5uA-4o8sA:
undetectable
6f5uB-4o8sA:
undetectable		 6f5uA-4o8sA:
20.00
6f5uB-4o8sA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4o8s PUTATIVE
(Helicobacter
pylori) 		5 / 10 ARG A  69
VAL A  70
ALA A  73
LEU A  66
LEU A 112
 None
 0.90A 6f6nA-4o8sA:
undetectable
6f6nB-4o8sA:
undetectable		 6f6nA-4o8sA:
20.00
6f6nB-4o8sA:
13.54