SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		5 / 8 VAL A 157
VAL A 167
LYS A 169
ILE A 267
ASP A 268
 GOL  A 401 ( 4.9A)
GOL  A 401 (-4.7A)
None
GOL  A 401 (-4.6A)
None
 1.11A 3warA-4o96A:
9.8		 3warA-4o96A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		4 / 6 ILE A 269
GLY A 152
ASN A 154
ILE A 267
 None
None
None
GOL  A 401 (-4.6A)
 0.93A 5j4nB-4o96A:
undetectable		 5j4nB-4o96A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		4 / 5 VAL A 167
PRO A 145
GLY A 146
TYR A 158
 GOL  A 401 (-4.7A)
None
None
None
 1.43A 5x80A-4o96A:
undetectable
5x80B-4o96A:
undetectable		 5x80A-4o96A:
21.11
5x80B-4o96A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		4 / 5 PRO A 145
GLY A 146
TYR A 158
VAL A 167
 None
None
None
GOL  A 401 (-4.7A)
 1.44A 5x80C-4o96A:
undetectable
5x80D-4o96A:
undetectable		 5x80C-4o96A:
21.11
5x80D-4o96A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		5 / 8 VAL A 157
VAL A 167
LYS A 169
ILE A 267
ASP A 268
 GOL  A 401 ( 4.9A)
GOL  A 401 (-4.7A)
None
GOL  A 401 (-4.6A)
None
 0.92A 5y9mX-4o96A:
8.5		 5y9mX-4o96A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		5 / 7 VAL A 157
VAL A 167
LYS A 169
ILE A 267
ASP A 268
 GOL  A 401 ( 4.9A)
GOL  A 401 (-4.7A)
None
GOL  A 401 (-4.6A)
None
 1.04A 5yf9B-4o96A:
9.2		 5yf9B-4o96A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		5 / 9 VAL A 157
VAL A 167
LYS A 169
ILE A 267
ASP A 268
 GOL  A 401 ( 4.9A)
GOL  A 401 (-4.7A)
None
GOL  A 401 (-4.6A)
None
 1.03A 5yf9X-4o96A:
8.7		 5yf9X-4o96A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		5 / 7 VAL A 157
VAL A 167
LYS A 169
ILE A 267
ASP A 268
 GOL  A 401 ( 4.9A)
GOL  A 401 (-4.7A)
None
GOL  A 401 (-4.6A)
None
 1.03A 5ywmX-4o96A:
9.3		 5ywmX-4o96A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4o96 TYPE III EFFECTOR
PROTEIN KINASE
(Escherichia
coli) 		4 / 6 ILE A 222
GLY A 216
TYR A 257
GLU A 217
 None
 1.10A 6gqiA-4o96A:
undetectable		 6gqiA-4o96A:
14.37