SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 4o9b STROMAL INTERACTION
MOLECULE 1
(Homo
sapiens) 		3 / 3 ARG A 287
LYS A 285
LYS A 284
 None
 1.41A 4k50A-4o9bA:
undetectable		 4k50A-4o9bA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 4o9b STROMAL INTERACTION
MOLECULE 1
(Homo
sapiens) 		3 / 3 ARG A 287
LYS A 285
LYS A 284
 None
 1.43A 4k50E-4o9bA:
undetectable		 4k50E-4o9bA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4o9b STROMAL INTERACTION
MOLECULE 1
(Homo
sapiens) 		4 / 4 VAL A 275
THR A 274
GLU A 271
GLU A 270
 None
 1.10A 4l78A-4o9bA:
undetectable		 4l78A-4o9bA:
6.87