SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 ASP B 304
LEU B 348
LEU B 346
 None
 0.68A 1ikeA-4o9dB:
undetectable		 1ikeA-4o9dB:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 ASP B 304
LEU B 348
LEU B 346
 None
 0.74A 1np1B-4o9dB:
undetectable		 1np1B-4o9dB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY B 565
ALA B 591
SER B 590
THR B 532
ILE B 549
 None
 1.20A 1nt2A-4o9dB:
undetectable		 1nt2A-4o9dB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ASP B 516
LEU B 502
VAL B 503
ILE B 496
 None
 0.93A 1s9qA-4o9dB:
undetectable		 1s9qA-4o9dB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 6 THR B 504
VAL B 514
LEU B 527
ALA B 552
 None
 1.05A 2e1qC-4o9dB:
undetectable		 2e1qC-4o9dB:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		6 / 12 VAL B 470
SER B 505
ALA B 552
THR B 563
ASN B 492
ILE B 549
 None
 1.42A 3a3bA-4o9dB:
undetectable		 3a3bA-4o9dB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 228
VAL B 572
ILE B 582
ARG B 576
 None
 0.93A 3pglA-4o9dB:
undetectable		 3pglA-4o9dB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PRO B 339
LEU B 366
LEU B 354
ILE B 343
 None
 0.94A 3u5jA-4o9dB:
undetectable		 3u5jA-4o9dB:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 5 TYR B 472
VAL B 503
SER B 517
GLY B 500
 None
 1.42A 3v4tA-4o9dB:
undetectable
3v4tD-4o9dB:
undetectable		 3v4tA-4o9dB:
21.50
3v4tD-4o9dB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 SER B 506
GLY B 507
GLN B 488
 None
 0.58A 3v4tH-4o9dB:
undetectable		 3v4tH-4o9dB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 4 TRP B 554
LEU B 575
LEU B 527
THR B 512
 None
 1.18A 4bboD-4o9dB:
undetectable		 4bboD-4o9dB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP B 414
SER B 392
HIS B 344
SER B 394
 None
 1.28A 4k7gB-4o9dB:
undetectable		 4k7gB-4o9dB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 GLU B 444
ALA B 445
PHE B 446
 None
 0.60A 4v1fA-4o9dB:
undetectable		 4v1fA-4o9dB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 GLU B 444
ALA B 445
PHE B 446
 None
 0.63A 4v1fC-4o9dB:
undetectable		 4v1fC-4o9dB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 5 THR B 504
ALA B 494
THR B 495
TYR B 450
 None
 1.36A 5ecmA-4o9dB:
undetectable		 5ecmA-4o9dB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP B 573
ILE B 549
SER B 506
 None
 0.78A 5gqbA-4o9dB:
undetectable		 5gqbA-4o9dB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 469
GLU B 444
PHE B 446
VAL B 480
 None
None
None
CL  B 705 (-4.5A)
 1.17A 5h4dA-4o9dB:
undetectable		 5h4dA-4o9dB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_H_BBIH405_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		4 / 4 ARG B 469
GLU B 444
PHE B 446
VAL B 480
 None
None
None
CL  B 705 (-4.5A)
 1.35A 5h4dH-4o9dB:
0.0		 5h4dH-4o9dB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B 354
THR B 368
ILE B 375
GLY B 334
ILE B 335
 None
 1.25A 5ifuA-4o9dB:
undetectable		 5ifuA-4o9dB:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4o9d RIK1-ASSOCIATED
FACTOR 1
(Schizosaccharomy
ces
pombe) 		5 / 12 ILE B 491
THR B 563
VAL B 570
VAL B 572
SER B 566
 None
 1.32A 6bzoC-4o9dB:
undetectable		 6bzoC-4o9dB:
16.98