SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.06A 1kiaA-4o9hL:
undetectable		 1kiaA-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.05A 1kiaB-4o9hL:
undetectable		 1kiaB-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.06A 1kiaC-4o9hL:
undetectable		 1kiaC-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.08A 1nbhB-4o9hL:
undetectable		 1nbhB-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.03A 1nbiA-4o9hL:
undetectable		 1nbiA-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		5 / 12 GLY L  23
VAL L   3
ALA L  74
TRP L  37
GLY L 102
 None
 1.03A 1nbiB-4o9hL:
undetectable		 1nbiB-4o9hL:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.26A 1zzrA-4o9hL:
undetectable
1zzrB-4o9hL:
undetectable		 1zzrA-4o9hL:
20.00
1zzrB-4o9hL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.26A 1zzuA-4o9hL:
undetectable
1zzuB-4o9hL:
undetectable		 1zzuA-4o9hL:
20.00
1zzuB-4o9hL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 GLU L  85
VAL L 108
ARG L  63
VAL L  18
 None
 1.27A 1zzuA-4o9hL:
undetectable
1zzuB-4o9hL:
undetectable		 1zzuA-4o9hL:
20.00
1zzuB-4o9hL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.21A 3jx2A-4o9hL:
undetectable
3jx2B-4o9hL:
undetectable		 3jx2A-4o9hL:
20.15
3jx2B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.24A 3jx5A-4o9hL:
undetectable
3jx5B-4o9hL:
undetectable		 3jx5A-4o9hL:
20.15
3jx5B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.20A 3jx6A-4o9hL:
undetectable
3jx6B-4o9hL:
undetectable		 3jx6A-4o9hL:
20.15
3jx6B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.21A 3nljA-4o9hL:
undetectable
3nljB-4o9hL:
undetectable		 3nljA-4o9hL:
20.15
3nljB-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.22A 3nlpA-4o9hL:
undetectable
3nlpB-4o9hL:
undetectable		 3nlpA-4o9hL:
20.15
3nlpB-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 8 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.21A 3nlqA-4o9hL:
undetectable
3nlqB-4o9hL:
undetectable		 3nlqA-4o9hL:
20.15
3nlqB-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.24A 3nlrA-4o9hL:
undetectable
3nlrB-4o9hL:
undetectable		 3nlrA-4o9hL:
20.15
3nlrB-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.28A 4cx3A-4o9hL:
undetectable
4cx3B-4o9hL:
undetectable		 4cx3A-4o9hL:
20.15
4cx3B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 GLU L  85
VAL L 108
ARG L  63
VAL L  18
 None
 1.26A 4cx3A-4o9hL:
undetectable
4cx3B-4o9hL:
undetectable		 4cx3A-4o9hL:
20.15
4cx3B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 VAL L 108
ARG L  63
VAL L  18
GLU L  85
 None
 1.27A 4cx4A-4o9hL:
undetectable
4cx4B-4o9hL:
undetectable		 4cx4A-4o9hL:
20.15
4cx4B-4o9hL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4o9h LIGHT CHAIN OF THE
CAMELID FAB FRAGMENT
61H7
(Lama
glama) 		4 / 7 GLU L  85
VAL L 108
ARG L  63
VAL L  18
 None
 1.24A 5addA-4o9hL:
undetectable
5addB-4o9hL:
undetectable		 5addA-4o9hL:
20.15
5addB-4o9hL:
20.15