SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4o9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE 2)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	4 / 8	GLY A 313 THR A 250 GLY A 253 GLN A 252	None	0.71A	1jr1B-4o9kA: undetectable	1jr1B-4o9kA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YZQ_A_SAMA6075_0 (PUTATIVE UNCHARACTERIZED PROTEIN PH1780)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 12	MET A 321 THR A 256 VAL A 254 ILE A 304 PRO A 308	None CMK A 401 (-3.4A) None CMK A 401 (-3.5A) CMK A 401 (-4.5A)	1.17A	2yzqA-4o9kA: 16.3	2yzqA-4o9kA: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 12	THR A 256 ASP A 259 THR A 280 ILE A 304 PRO A 308	CMK A 401 (-3.4A) CMK A 401 (-2.6A) CMK A 401 (-3.1A) CMK A 401 (-3.5A) CMK A 401 (-4.5A)	0.65A	3kpbA-4o9kA: 16.3	3kpbA-4o9kA: 29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_C_SAMC1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 12	THR A 256 ASP A 259 THR A 280 ILE A 304 PRO A 308	CMK A 401 (-3.4A) CMK A 401 (-2.6A) CMK A 401 (-3.1A) CMK A 401 (-3.5A) CMK A 401 (-4.5A)	0.68A	3kpbC-4o9kA: 16.4	3kpbC-4o9kA: 29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 11	THR A 256 ASP A 259 THR A 280 ILE A 304 PRO A 308	CMK A 401 (-3.4A) CMK A 401 (-2.6A) CMK A 401 (-3.1A) CMK A 401 (-3.5A) CMK A 401 (-4.5A)	0.69A	3kpcA-4o9kA: 17.8	3kpcA-4o9kA: 28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_B_SAMB1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 12	THR A 256 ASP A 259 THR A 280 ILE A 304 PRO A 308	CMK A 401 (-3.4A) CMK A 401 (-2.6A) CMK A 401 (-3.1A) CMK A 401 (-3.5A) CMK A 401 (-4.5A)	0.58A	3kpdB-4o9kA: 16.5	3kpdB-4o9kA: 29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPD_C_SAMC1000_1 (UNCHARACTERIZED PROTEIN MJ0100)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	5 / 12	THR A 256 ASP A 259 THR A 280 ILE A 304 PRO A 308	CMK A 401 (-3.4A) CMK A 401 (-2.6A) CMK A 401 (-3.1A) CMK A 401 (-3.5A) CMK A 401 (-4.5A)	0.62A	3kpdC-4o9kA: 17.5	3kpdC-4o9kA: 29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_A_C2FA1100_1 (GLYCINE N-METHYLTRANSFERASE)	4o9k	ARABINOSE 5-PHOSPHATE ISOMERASE (Methylococcus capsulatus)	3 / 3	LEU A 325 HIS A 322 MET A 321	None	0.96A	3thrD-4o9kA: undetectable	3thrD-4o9kA: 20.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JR1_B_MOAB1333_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",4,"GLY A 313;THR A 250;GLY A 253;GLN A 252","None","0.71A","1jr1B-4o9kA:undetectable","1jr1B-4o9kA:16.01"],["2YZQ_A_SAMA6075_0","PUTATIVE UNCHARACTERIZED PROTEIN PH1780","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"MET A 321;THR A 256;VAL A 254;ILE A 304;PRO A 308","None;CMK A 401 (-3.4A);None;CMK A 401 (-3.5A);CMK A 401 (-4.5A)","1.17A","2yzqA-4o9kA:16.3","2yzqA-4o9kA:22.18"],["3KPB_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"THR A 256;ASP A 259;THR A 280;ILE A 304;PRO A 308","CMK A 401 (-3.4A);CMK A 401 (-2.6A);CMK A 401 (-3.1A);CMK A 401 (-3.5A);CMK A 401 (-4.5A)","0.65A","3kpbA-4o9kA:16.3","3kpbA-4o9kA:29.50"],["3KPB_C_SAMC1000_0","UNCHARACTERIZED PROTEIN MJ0100","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"THR A 256;ASP A 259;THR A 280;ILE A 304;PRO A 308","CMK A 401 (-3.4A);CMK A 401 (-2.6A);CMK A 401 (-3.1A);CMK A 401 (-3.5A);CMK A 401 (-4.5A)","0.68A","3kpbC-4o9kA:16.4","3kpbC-4o9kA:29.50"],["3KPC_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"THR A 256;ASP A 259;THR A 280;ILE A 304;PRO A 308","CMK A 401 (-3.4A);CMK A 401 (-2.6A);CMK A 401 (-3.1A);CMK A 401 (-3.5A);CMK A 401 (-4.5A)","0.69A","3kpcA-4o9kA:17.8","3kpcA-4o9kA:28.47"],["3KPD_B_SAMB1000_0","UNCHARACTERIZED PROTEIN MJ0100","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"THR A 256;ASP A 259;THR A 280;ILE A 304;PRO A 308","CMK A 401 (-3.4A);CMK A 401 (-2.6A);CMK A 401 (-3.1A);CMK A 401 (-3.5A);CMK A 401 (-4.5A)","0.58A","3kpdB-4o9kA:16.5","3kpdB-4o9kA:29.50"],["3KPD_C_SAMC1000_1","UNCHARACTERIZED PROTEIN MJ0100","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",5,"THR A 256;ASP A 259;THR A 280;ILE A 304;PRO A 308","CMK A 401 (-3.4A);CMK A 401 (-2.6A);CMK A 401 (-3.1A);CMK A 401 (-3.5A);CMK A 401 (-4.5A)","0.62A","3kpdC-4o9kA:17.5","3kpdC-4o9kA:29.50"],["3THR_A_C2FA1100_1","GLYCINE N-METHYLTRANSFERASE","4o9k","ARABINOSE 5-PHOSPHATE ISOMERASE","Methylococcus capsulatus",3,"LEU A 325;HIS A 322;MET A 321","None","0.96A","3thrD-4o9kA:undetectable","3thrD-4o9kA:20.89"]]