SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 4 ARG A 267
ALA A 271
ALA A  58
GLU A  62
 None
 1.08A 1e7bA-4oanA:
undetectable		 1e7bA-4oanA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 4 ARG A 267
ALA A 271
ALA A  58
GLU A  62
 None
 1.02A 1e7bB-4oanA:
undetectable		 1e7bB-4oanA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 117
ILE A 166
THR A 159
LEU A 100
LEU A 310
 None
 1.20A 1eiiA-4oanA:
undetectable		 1eiiA-4oanA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 118
GLY A  99
ALA A 109
GLY A 133
LEU A 132
 None
 0.98A 1igxA-4oanA:
undetectable		 1igxA-4oanA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 138
LEU A  84
VAL A 147
LEU A 248
LEU A 105
 None
 1.25A 1jipA-4oanA:
undetectable		 1jipA-4oanA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 155
ASN A 218
ILE A 101
LEU A  84
LEU A  42
 None
X2X  A 402 (-2.8A)
None
None
None
 1.20A 1r30A-4oanA:
undetectable		 1r30A-4oanA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 155
ASN A 218
ILE A 101
LEU A  84
LEU A  42
 None
X2X  A 402 (-2.8A)
None
None
None
 1.20A 1r30B-4oanA:
undetectable		 1r30B-4oanA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 MET A 188
ILE A 114
PRO A 180
SER A 198
 None
None
X2X  A 402 (-4.1A)
GOL  A 403 (-2.6A)
 1.48A 2qd3B-4oanA:
undetectable		 2qd3B-4oanA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 114
ILE A 177
THR A 238
PHE A 116
HIS A 240
 None
 1.14A 2qo5A-4oanA:
undetectable		 2qo5A-4oanA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 101
GLU A 217
ASP A 243
GLY A  99
 None
 0.92A 2qqdB-4oanA:
undetectable
2qqdC-4oanA:
undetectable		 2qqdB-4oanA:
17.07
2qqdC-4oanA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 9 VAL A 106
LEU A  84
ILE A  87
ILE A 151
GLY A 133
 None
 1.05A 3cv9A-4oanA:
undetectable		 3cv9A-4oanA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 4 ASP A  80
SER A  98
PHE A 245
SER A  74
 X2X  A 402 ( 4.8A)
X2X  A 402 ( 4.5A)
X2X  A 402 (-4.7A)
None
 1.48A 3i5uA-4oanA:
undetectable		 3i5uA-4oanA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 ARG A 311
ILE A 114
THR A 123
 None
 0.56A 3ia4D-4oanA:
undetectable		 3ia4D-4oanA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 ASN A 268
ASN A 275
GLU A  54
 None
 0.88A 3kpdC-4oanA:
undetectable		 3kpdC-4oanA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 118
GLY A  99
ALA A 109
GLY A 133
LEU A 132
 None
 0.99A 4e1gA-4oanA:
undetectable		 4e1gA-4oanA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 118
ILE A 151
ALA A 108
GLY A 133
LEU A 132
 None
 0.90A 4e1gA-4oanA:
undetectable		 4e1gA-4oanA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PHE A 118
GLY A  99
ALA A 109
GLY A 133
LEU A 132
 None
 0.99A 4e1gB-4oanA:
undetectable		 4e1gB-4oanA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.89A 4k8cA-4oanA:
undetectable		 4k8cA-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.90A 4kahA-4oanA:
undetectable		 4kahA-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.89A 4kahB-4oanA:
undetectable		 4kahB-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.91A 4kanA-4oanA:
undetectable		 4kanA-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.88A 4kanB-4oanA:
undetectable		 4kanB-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.86A 4kbeA-4oanA:
undetectable		 4kbeA-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.84A 4kbeB-4oanA:
undetectable		 4kbeB-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.92A 4lbgA-4oanA:
undetectable		 4lbgA-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 SER A 224
TYR A 229
PRO A  43
 None
 0.91A 4lbgB-4oanA:
undetectable		 4lbgB-4oanA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 5 LEU A  97
LEU A 100
LEU A  84
ASN A 112
 None
 0.99A 4n09B-4oanA:
undetectable		 4n09B-4oanA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 7 ASN A 218
PRO A 219
TRP A 185
PHE A 189
 X2X  A 402 (-2.8A)
None
None
None
 1.36A 4v32B-4oanA:
undetectable		 4v32B-4oanA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 5 TYR A 229
LYS A 294
LEU A 287
GLU A 290
 None
 1.43A 4z4hA-4oanA:
undetectable		 4z4hA-4oanA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 LEU A 287
PHE A 298
ILE A 223
 None
 0.73A 5dzk1-4oanA:
undetectable
5dzkF-4oanA:
undetectable
5dzkM-4oanA:
undetectable		 5dzk1-4oanA:
0.62
5dzkF-4oanA:
22.32
5dzkM-4oanA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4oan TRAP DICARBOXYLATE
TRANSPORTER DCTP
SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 222
GLY A 244
ILE A  50
ALA A  52
THR A  96
 None
 1.00A 5e72A-4oanA:
undetectable		 5e72A-4oanA:
25.00