SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ob1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		3 / 3 PHE A 168
SER A 163
SER A 164
 None
 1.02A 3ufgB-4ob1A:
undetectable		 3ufgB-4ob1A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		4 / 8 ILE A  85
PRO A 172
VAL A  60
TRP A  63
 None
 1.29A 4f4dB-4ob1A:
undetectable		 4f4dB-4ob1A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		5 / 6 LEU A  83
ARG A  71
ASP A  65
VAL A 190
ALA A 187
 None
 1.15A 4nkxA-4ob1A:
undetectable		 4nkxA-4ob1A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		5 / 12 LEU A  54
GLY A  55
MET A 195
ILE A 196
VAL A 106
 None
 1.21A 4okwA-4ob1A:
undetectable		 4okwA-4ob1A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		3 / 3 GLY A  51
VAL A 169
MET A 195
 None
 0.52A 5ycpA-4ob1A:
undetectable		 5ycpA-4ob1A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 4ob1 COBALT-CONTAINING
NITRILE HYDRATASE
SUBUNIT ALPHA
(Pseudonocardia
thermophila) 		5 / 12 GLY A  76
ASP A  92
GLY A  87
GLY A  86
ILE A  85
 None
 0.77A 6dj1A-4ob1A:
undetectable		 6dj1A-4ob1A:
15.30