SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4obm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 7 GLY A 113
ALA A 274
THR A 280
THR A  67
 None
 0.72A 1c9sT-4obmA:
undetectable
1c9sU-4obmA:
undetectable		 1c9sT-4obmA:
16.02
1c9sU-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 7 GLY A 113
ALA A 274
THR A 280
THR A  67
 None
 0.69A 1gtfL-4obmA:
undetectable
1gtfM-4obmA:
undetectable		 1gtfL-4obmA:
16.02
1gtfM-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 GLY A 113
ALA A 274
THR A 280
THR A  67
 None
 0.68A 1gtfN-4obmA:
undetectable
1gtfO-4obmA:
undetectable		 1gtfN-4obmA:
16.02
1gtfO-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 7 GLY A 113
ALA A 274
THR A 280
THR A  67
 None
 0.64A 1gtnA-4obmA:
undetectable
1gtnK-4obmA:
undetectable		 1gtnA-4obmA:
16.02
1gtnK-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 THR A  67
GLY A 113
ALA A 274
THR A 280
 None
 0.67A 1gtnE-4obmA:
undetectable
1gtnF-4obmA:
undetectable		 1gtnE-4obmA:
16.02
1gtnF-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 5 SER A 110
ASP A 268
ASP A 258
ILE A 265
 None
 1.40A 3uj7B-4obmA:
undetectable		 3uj7B-4obmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 THR A  67
GLY A 113
ALA A 274
THR A 280
 None
 0.70A 5eezL-4obmA:
undetectable
5eezV-4obmA:
undetectable		 5eezL-4obmA:
16.02
5eezV-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 THR A  67
GLY A 113
ALA A 274
THR A 280
 None
 0.70A 5ef1L-4obmA:
undetectable
5ef1V-4obmA:
undetectable		 5ef1L-4obmA:
16.02
5ef1V-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 THR A  67
GLY A 113
ALA A 274
THR A 280
 None
 0.70A 5ef2L-4obmA:
undetectable
5ef2V-4obmA:
undetectable		 5ef2L-4obmA:
16.02
5ef2V-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 THR A  67
GLY A 113
ALA A 274
THR A 280
 None
 0.70A 5ef3L-4obmA:
undetectable
5ef3V-4obmA:
undetectable		 5ef3L-4obmA:
16.02
5ef3V-4obmA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 8 ILE A  66
MET A 133
LEU A 211
TYR A  68
 None
 1.03A 5ieoA-4obmA:
undetectable		 5ieoA-4obmA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 4obm UNCHARACTERIZED
PROTEIN
([Eubacterium]
siraeum) 		4 / 4 GLN A 163
VAL A 141
GLU A 144
ILE A 145
 None
 1.44A 5jncA-4obmA:
undetectable		 5jncA-4obmA:
20.42