SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		6 / 11 ILE A 401
ALA A 399
GLU A 345
PHE A 344
PRO A 310
ILE A 355
 None
 1.46A 1dyrA-4oc9A:
undetectable		 1dyrA-4oc9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ILE A 166
ALA A 170
PHE A 150
ILE A 199
ILE A 163
 None
 1.21A 1j3jA-4oc9A:
undetectable		 1j3jA-4oc9A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ILE A 312
LEU A 342
PHE A 344
ILE A 375
PRO A 378
 None
 0.91A 1jolB-4oc9A:
undetectable		 1jolB-4oc9A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ILE A 312
LEU A 342
PHE A 344
ILE A 375
PRO A 378
 None
 0.95A 1re7B-4oc9A:
undetectable		 1re7B-4oc9A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ILE A 312
LEU A 342
PHE A 344
ILE A 375
PRO A 378
 None
 0.97A 1rx8A-4oc9A:
undetectable		 1rx8A-4oc9A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 11 SER A 258
PHE A  76
ALA A  69
PHE A 192
VAL A 198
 None
 1.11A 1ukbA-4oc9A:
undetectable		 1ukbA-4oc9A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 ALA A 338
TYR A 206
ILE A 292
LEU A 153
 None
 1.05A 1xvaA-4oc9A:
2.9
1xvaB-4oc9A:
undetectable		 1xvaA-4oc9A:
21.35
1xvaB-4oc9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 GLY A 215
VAL A 207
LEU A 273
SER A  61
LEU A 218
 None
 1.06A 1ya4C-4oc9A:
undetectable		 1ya4C-4oc9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 11 ILE A 166
ALA A 170
PHE A 150
ILE A 199
ILE A 163
 None
 1.26A 2blaA-4oc9A:
undetectable		 2blaA-4oc9A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ILE A 312
LEU A 342
PHE A 344
ILE A 375
PRO A 378
 None
 0.96A 2d0kA-4oc9A:
undetectable		 2d0kA-4oc9A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ASP A 241
LEU A 249
ALA A 236
ASN A 248
PHE A 257
 None
 1.16A 2ejtA-4oc9A:
undetectable		 2ejtA-4oc9A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 SER A 152
LEU A 189
ASP A 180
GLU A  72
 None
None
LLP  A 205 ( 3.2A)
None
 1.12A 2j2pE-4oc9A:
undetectable
2j2pF-4oc9A:
undetectable		 2j2pE-4oc9A:
17.72
2j2pF-4oc9A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ALA A 399
GLU A 345
PHE A 344
LEU A 417
THR A 397
 None
 1.19A 2w3aB-4oc9A:
undetectable		 2w3aB-4oc9A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ILE A 166
ALA A 170
PHE A 149
PHE A 150
ILE A 199
 None
 1.24A 2w3aB-4oc9A:
undetectable		 2w3aB-4oc9A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 399
GLU A 345
PHE A 344
LEU A 417
THR A 397
 None
 1.23A 2w3mB-4oc9A:
undetectable		 2w3mB-4oc9A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 5 ILE A  78
THR A 264
PHE A  88
TYR A  89
 None
 1.29A 3em0A-4oc9A:
undetectable		 3em0A-4oc9A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 THR A 185
LEU A 188
SER A 296
HIS A 295
 None
 0.82A 3kp2A-4oc9A:
1.6
3kp2B-4oc9A:
undetectable		 3kp2A-4oc9A:
17.26
3kp2B-4oc9A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 9 VAL A 261
ILE A  78
PHE A  76
ALA A  75
VAL A 198
 None
 1.26A 3me6D-4oc9A:
undetectable		 3me6D-4oc9A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ILE A 166
ALA A 170
PHE A 150
ILE A 199
ILE A 163
 None
 1.19A 3qgtA-4oc9A:
undetectable		 3qgtA-4oc9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ILE A 166
ALA A 170
PHE A 150
ILE A 199
ILE A 163
 None
 1.27A 3qgtB-4oc9A:
undetectable		 3qgtB-4oc9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 5 LEU A 224
ARG A 221
ILE A 175
ARG A 233
 None
 1.16A 3ticA-4oc9A:
undetectable		 3ticA-4oc9A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 159
GLY A 395
ALA A 379
ASN A 316
PRO A 156
 None
 1.29A 3tm4A-4oc9A:
3.5		 3tm4A-4oc9A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 159
GLY A 395
ALA A 379
ASN A 316
PRO A 156
 None
 1.27A 3tm4B-4oc9A:
3.3		 3tm4B-4oc9A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 399
GLU A 345
PHE A 344
LEU A 417
THR A 397
 None
 1.24A 4cd2A-4oc9A:
undetectable		 4cd2A-4oc9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 5 GLY A  77
ILE A  78
VAL A 198
SER A 258
 None
 1.13A 4d33A-4oc9A:
undetectable		 4d33A-4oc9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 5 GLY A  77
ILE A  78
VAL A 198
SER A 258
 None
 1.15A 4d33B-4oc9A:
undetectable		 4d33B-4oc9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ALA A 399
GLU A 345
PHE A 344
ILE A 355
THR A 397
 None
 1.17A 4g8zX-4oc9A:
undetectable		 4g8zX-4oc9A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 10 ILE A 401
ALA A 399
GLU A 345
PHE A 344
ILE A 355
 None
 1.29A 4g8zX-4oc9A:
undetectable		 4g8zX-4oc9A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 ILE A 148
ILE A 163
PHE A 129
LEU A 134
 None
 0.85A 4m51A-4oc9A:
undetectable		 4m51A-4oc9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 ASP A  62
ASN A  29
ALA A  31
TYR A  53
 None
 0.99A 4mdbA-4oc9A:
undetectable		 4mdbA-4oc9A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 217
GLY A 216
SER A  82
ILE A  78
GLY A  65
 None
None
LLP  A 205 ( 3.7A)
None
None
 1.18A 4obwA-4oc9A:
3.0		 4obwA-4oc9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 9 ASP A 197
VAL A 196
ALA A 170
PHE A 150
ILE A 148
 None
 1.39A 4oknB-4oc9A:
2.3		 4oknB-4oc9A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 161
TYR A 332
LEU A 134
SER A 177
ILE A 148
 None
 1.19A 4pb1A-4oc9A:
undetectable		 4pb1A-4oc9A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 161
TYR A 332
LEU A 134
SER A 177
ILE A 148
 None
 1.25A 4pd5A-4oc9A:
undetectable		 4pd5A-4oc9A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ALA A 161
TYR A 332
LEU A 134
SER A 177
ILE A 148
 None
 1.13A 4pd9A-4oc9A:
undetectable		 4pd9A-4oc9A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 GLY A  77
ILE A 199
HIS A 201
GLY A  74
GLY A  12
 None
 0.90A 5d4uA-4oc9A:
4.0		 5d4uA-4oc9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 GLY A  77
ILE A 199
HIS A 201
GLY A  74
GLY A  12
 None
 0.87A 5d4uB-4oc9A:
4.0		 5d4uB-4oc9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 GLY A  77
ILE A 199
HIS A 201
GLY A  74
GLY A  12
 None
 0.88A 5d4uC-4oc9A:
3.8		 5d4uC-4oc9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 GLY A  77
ILE A 199
HIS A 201
GLY A  74
GLY A  12
 None
 0.96A 5d4uD-4oc9A:
undetectable		 5d4uD-4oc9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 12 ILE A 312
LEU A 342
PHE A 344
ILE A 375
PRO A 378
 None
 0.96A 5eajB-4oc9A:
undetectable		 5eajB-4oc9A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		3 / 3 GLY A 395
GLN A 392
LYS A 106
 None
 1.00A 5imsB-4oc9A:
3.6		 5imsB-4oc9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 ARG A 291
HIS A 295
LEU A 368
SER A 208
 None
None
LLP  A 205 ( 4.2A)
LLP  A 205 ( 4.6A)
 1.17A 5syjA-4oc9A:
undetectable		 5syjA-4oc9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 ARG A 291
HIS A 295
LEU A 368
SER A 208
 None
None
LLP  A 205 ( 4.2A)
LLP  A 205 ( 4.6A)
 1.22A 5syjB-4oc9A:
undetectable		 5syjB-4oc9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		5 / 11 ILE A 163
ASN A 181
VAL A 200
SER A 177
ASP A 180
 None
None
None
None
LLP  A 205 ( 3.2A)
 1.50A 5z0hA-4oc9A:
undetectable
5z0hB-4oc9A:
undetectable		 5z0hA-4oc9A:
11.82
5z0hB-4oc9A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 6 VAL A 196
TYR A 332
ILE A 163
GLU A 164
 None
 0.98A 5z3jA-4oc9A:
undetectable		 5z3jA-4oc9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 ASP A 142
ILE A 141
ARG A 127
TYR A 103
 None
 1.24A 6hisA-4oc9A:
undetectable
6hisB-4oc9A:
undetectable		 6hisA-4oc9A:
12.07
6hisB-4oc9A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 ASP A 142
ILE A 141
ARG A 127
TYR A 103
 None
 1.25A 6hisB-4oc9A:
undetectable
6hisC-4oc9A:
undetectable		 6hisB-4oc9A:
12.07
6hisC-4oc9A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 ASP A 142
ILE A 141
ARG A 127
TYR A 103
 None
 1.25A 6hisC-4oc9A:
undetectable
6hisD-4oc9A:
undetectable		 6hisC-4oc9A:
12.07
6hisD-4oc9A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 ASP A 142
ILE A 141
ARG A 127
TYR A 103
 None
 1.24A 6hisD-4oc9A:
undetectable
6hisE-4oc9A:
undetectable		 6hisD-4oc9A:
12.07
6hisE-4oc9A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE
(Campylobacter
jejuni) 		4 / 8 TYR A 103
ASP A 142
ILE A 141
ARG A 127
 None
 1.26A 6hisA-4oc9A:
undetectable
6hisE-4oc9A:
undetectable		 6hisA-4oc9A:
12.07
6hisE-4oc9A:
12.07