SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ocr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ocr CAP256-VRC26.01
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
 None
 0.60A 3qxvA-4ocrH:
21.4		 3qxvA-4ocrH:
54.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4ocr CAP256-VRC26.01
HEAVY CHAIN
(Homo
sapiens) 		5 / 11 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
 None
 0.53A 3qxvC-4ocrH:
21.7		 3qxvC-4ocrH:
54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4ocr CAP256-VRC26.01
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.74A 5ecmD-4ocrH:
undetectable		 5ecmD-4ocrH:
17.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 4ocr CAP256-VRC26.01
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-4ocrH:
19.3		 6cjkB-4ocrH:
53.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ocr CAP256-VRC26.01
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.44A 6h7mB-4ocrH:
undetectable		 6h7mB-4ocrH:
14.45