SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ocs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.43A 2y03A-4ocsH:
undetectable		 2y03A-4ocsH:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.48A 2y03B-4ocsH:
undetectable		 2y03B-4ocsH:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ASP H  95
GLY H 100
TYR H  99
HIS H  35
 None
 0.90A 3af0A-4ocsH:
undetectable		 3af0A-4ocsH:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR H 110
GLU H 148
HIS H 200
 None
 0.78A 3g1uB-4ocsH:
undetectable		 3g1uB-4ocsH:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 PRO H 185
SER H 187
SER H 188
 None
 0.68A 6bpyA-4ocsH:
undetectable		 6bpyA-4ocsH:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ocs CAP256-VRC26.10
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.45A 6h7mB-4ocsH:
undetectable		 6h7mB-4ocsH:
16.41