SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4odw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		3 / 3 TRP H  36
ALA H  50
VAL H  48
 None
 0.97A 1bdwA-4odwH:
undetectable
1bdwB-4odwH:
undetectable		 1bdwA-4odwH:
6.62
1bdwB-4odwH:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 146
THR H 116
PRO H 118
 None
 1.34A 1dsdC-4odwH:
undetectable		 1dsdC-4odwH:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 146
THR H 116
PRO H 118
 None
 1.34A 1dsdC-4odwH:
undetectable		 1dsdC-4odwH:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		6 / 11 PHE H  29
ASN H  73
GLY H  54
THR H  57
ILE H  69
LEU H  78
 None
 1.38A 1z11A-4odwH:
undetectable		 1z11A-4odwH:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		5 / 11 LEU H 137
VAL H 162
GLY H 156
VAL H 182
VAL H 180
 None
 1.07A 2nnpB-4odwH:
undetectable		 2nnpB-4odwH:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4odw A6 FAB (IGG2B) HEAVY
CHAIN
(Mus
musculus) 		5 / 12 GLU H  42
ALA H  88
THR H  93
ARG H  44
LEU H  45
 None
 1.29A 5m54B-4odwH:
undetectable		 5m54B-4odwH:
19.65