SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oe1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 11 ALA A 113
LEU A 114
LEU A 110
LEU A 102
ALA A  82
 None
 1.17A 1h9zA-4oe1A:
undetectable		 1h9zA-4oe1A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 4 ARG A 688
LEU A 654
ASN A 655
VAL A 689
 None
 1.06A 1lqtA-4oe1A:
undetectable		 1lqtA-4oe1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1875_0
(FPRA)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 4 ARG A 688
LEU A 654
ASN A 655
VAL A 689
 None
 1.08A 1lqtB-4oe1A:
undetectable		 1lqtB-4oe1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 4 ARG A 688
LEU A 654
ASN A 655
VAL A 689
 None
 1.08A 1lquA-4oe1A:
undetectable		 1lquA-4oe1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1432_0
(FPRA)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 4 ARG A 688
LEU A 654
ASN A 655
VAL A 689
 None
 1.08A 1lquB-4oe1A:
undetectable		 1lquB-4oe1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 7 VAL A 391
LEU A 390
ALA A 369
LEU A 370
 None
 0.74A 1pthA-4oe1A:
undetectable		 1pthA-4oe1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 7 VAL A 391
LEU A 390
ALA A 369
LEU A 370
 None
 0.74A 1pthB-4oe1A:
undetectable		 1pthB-4oe1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 6 LEU A 443
THR A 482
TYR A 458
TYR A 465
 None
 1.49A 1qvuA-4oe1A:
undetectable		 1qvuA-4oe1A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		3 / 3 ARG A 447
ASN A 419
THR A 457
 None
 0.79A 2q63A-4oe1A:
undetectable		 2q63A-4oe1A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 7 THR A 358
GLY A 361
ASN A 362
GLY A 323
THR A 324
 None
 1.37A 3tajA-4oe1A:
undetectable		 3tajA-4oe1A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 12 LEU A 531
TYR A 528
ALA A 570
ALA A 536
TYR A 535
 None
 1.08A 3vw7A-4oe1A:
undetectable		 3vw7A-4oe1A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 8 VAL A 265
TYR A 283
VAL A 261
ILE A 252
 None
 1.14A 4aftD-4oe1A:
undetectable
4aftE-4oe1A:
undetectable		 4aftD-4oe1A:
15.19
4aftE-4oe1A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 5 GLY A 469
GLY A 466
ASN A 498
GLU A 436
 None
 1.30A 4fglC-4oe1A:
undetectable		 4fglC-4oe1A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 7 TYR A 478
ILE A 512
TYR A 493
PRO A 488
 None
 1.10A 4g5jA-4oe1A:
undetectable		 4g5jA-4oe1A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 8 GLU A 163
ASP A 162
ARG A 189
TRP A 120
 None
 1.22A 4uhxA-4oe1A:
undetectable		 4uhxA-4oe1A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 10 HIS A 276
ALA A 248
SER A 249
PHE A 267
LEU A 233
 None
None
A  C   3 ( 2.6A)
None
None
 1.43A 5mm4B-4oe1A:
undetectable		 5mm4B-4oe1A:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 12 LEU A 111
ASP A 106
ALA A 135
PRO A 167
LEU A 166
 None
 1.27A 5syfB-4oe1A:
undetectable		 5syfB-4oe1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		4 / 5 VAL A 210
THR A 208
VAL A 157
LEU A 184
 U  C   2 ( 3.7A)
G  C   1 ( 3.9A)
None
None
 0.83A 6bqgA-4oe1A:
undetectable		 6bqgA-4oe1A:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4oe1 CHLOROPLAST
PENTATRICOPEPTIDE
REPEAT PROTEIN 10
(Zea
mays) 		5 / 10 LEU A 160
GLY A 149
LEU A 148
GLN A 153
VAL A 180
 None
 1.14A 6czmE-4oe1A:
undetectable
6czmF-4oe1A:
undetectable		 6czmE-4oe1A:
19.34
6czmF-4oe1A:
19.34