SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4oe6'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LHV_A_NOGA301_1 (SEX HORMONE-BINDING GLOBULIN)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 8	SER A 407 THR A 343 ASN A 322 LEU A 411	None	0.94A	1lhvA-4oe6A: undetectable	1lhvA-4oe6A: 14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RE7_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	ALA A 447 LYS A 420 THR A 443 ILE A 415 ILE A 426	None	1.14A	1re7A-4oe6A: undetectable	1re7A-4oe6A: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_E_TRPE81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 430 ALA A 418 THR A 443 ILE A 426 GLY A 461	None	1.01A	1utdE-4oe6A: undetectable 1utdF-4oe6A: undetectable	1utdE-4oe6A: 8.98 1utdF-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FXD_A_DR7A102_1 (POL PROTEIN)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 11	ILE A 374 LEU A 375 GLY A 441 ILE A 445 PHE A 372	None	1.02A	2fxdA-4oe6A: undetectable	2fxdA-4oe6A: 11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNK_A_ROCA401_3 (PROTEASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	LEU A 464 GLY A 373 ILE A 374 PRO A 442 VAL A 444	None	0.82A	2nnkB-4oe6A: undetectable	2nnkB-4oe6A: 10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFS_A_J01A500_1 (ORF12)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 8	VAL A 208 LEU A  63 GLY A 265 ALA A  97	None	0.89A	2xfsA-4oe6A: undetectable	2xfsA-4oe6A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BC9_A_ACRA901_1 (ALPHA AMYLASE, CATALYTIC REGION)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 7	ASP A 370 SER A 369 SER A 364 ASP A 471	None	1.14A	3bc9A-4oe6A: undetectable	3bc9A-4oe6A: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWM_A_SAMA301_0 (CATECHOL O-METHYLTRANSFERASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	VAL A 155 GLY A 152 TYR A 156 ILE A 403 ASN A 212	None	1.50A	3bwmA-4oe6A: 4.3	3bwmA-4oe6A: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB924_0 (FERROCHELATASE, MITOCHONDRIAL)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	PRO A 401 VAL A 440 GLY A 441 PRO A 442 MET A 399	None	1.40A	3hcoB-4oe6A: undetectable	3hcoB-4oe6A: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HUO_A_PNNA304_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 4	GLN A 184 PRO A 185 VAL A 186 GLU A 187	None	0.71A	3huoA-4oe6A: undetectable	3huoA-4oe6A: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SMT_A_ACTA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD3)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	PHE A 439 SER A 435 GLN A 436	None	0.91A	3smtA-4oe6A: undetectable	3smtA-4oe6A: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SO9_A_017A100_2 (HIV-1 PROTEASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	LEU A 464 GLY A 373 ILE A 374 PRO A 442 VAL A 444	None	0.85A	3so9B-4oe6A: undetectable	3so9B-4oe6A: 10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQ6_A_ADNA401_2 (ADENOSINE KINASE, PUTATIVE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 5	LEU A 220 ALA A 215 PHE A 169 ASN A 212	None	1.40A	3uq6A-4oe6A: undetectable	3uq6A-4oe6A: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAQ_A_ADNA401_2 (PUTATIVE ADENOSINE KINASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 4	LEU A 220 ALA A 215 PHE A 169 ASN A 212	None	1.37A	3vaqA-4oe6A: 3.2	3vaqA-4oe6A: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAS_A_ADNA401_2 (PUTATIVE ADENOSINE KINASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 4	LEU A 220 ALA A 215 PHE A 169 ASN A 212	None	1.39A	3vasA-4oe6A: undetectable	3vasA-4oe6A: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOV_A_KOVA204_1 (UNCHARACTERIZED PROTEIN)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	TYR A 311 PRO A 312 GLY A 306 PHE A 280 LEU A 275	None	1.30A	4kovA-4oe6A: undetectable	4kovA-4oe6A: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB305_1 (CHITOSANASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	GLY A 400 PRO A 401 GLN A 349	None	0.52A	4qwpB-4oe6A: 0.0	4qwpB-4oe6A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_A_RTLA201_1 (RETINOL-BINDING PROTEIN 2)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	PHE A 367 THR A 522 LEU A 464	None	0.70A	4qztA-4oe6A: undetectable	4qztA-4oe6A: 14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WOZ_B_MN9B401_0 (N-ACETYLNEURAMINATE LYASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 6	SER A 550 LEU A 549 TYR A 181 LEU A 180	None	1.04A	4wozA-4oe6A: undetectable 4wozB-4oe6A: undetectable	4wozA-4oe6A: 20.63 4wozB-4oe6A: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_B_SAMB301_1 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	ASP A 142 GLU A 252 SER A  57	None	0.81A	5bw4B-4oe6A: 3.4	5bw4B-4oe6A: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5eevA-4oe6A: undetectable 5eevB-4oe6A: undetectable	5eevA-4oe6A: 8.98 5eevB-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.00A	5eewA-4oe6A: undetectable 5eewB-4oe6A: undetectable	5eewA-4oe6A: 8.98 5eewB-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5eexA-4oe6A: undetectable 5eexB-4oe6A: undetectable	5eexA-4oe6A: 8.98 5eexB-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5eeyA-4oe6A: undetectable 5eeyB-4oe6A: undetectable	5eeyA-4oe6A: 8.98 5eeyB-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5eezA-4oe6A: undetectable 5eezB-4oe6A: undetectable	5eezA-4oe6A: 8.98 5eezB-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5ef0A-4oe6A: undetectable 5ef0B-4oe6A: undetectable	5ef0A-4oe6A: 8.98 5ef0B-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5ef1A-4oe6A: undetectable 5ef1B-4oe6A: undetectable	5ef1A-4oe6A: 8.98 5ef1B-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5ef2A-4oe6A: undetectable 5ef2B-4oe6A: undetectable	5ef2A-4oe6A: 8.98 5ef2B-4oe6A: 8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_A_TRPA101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4oe6	DELTA-1-PYRROLINE-5- CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 10	GLY A 461 GLY A 430 ALA A 418 THR A 443 ILE A 426	None	1.01A	5ef3A-4oe6A: undetectable 5ef3B-4oe6A: undetectable	5ef3A-4oe6A: 8.98 5ef3B-4oe6A: 8.98