SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4of8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 8 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.99A 2qd5A-4of8A:
undetectable		 2qd5A-4of8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 8 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.88A 2qd5B-4of8A:
undetectable		 2qd5B-4of8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 7 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.80A 3hcnA-4of8A:
undetectable		 3hcnA-4of8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 8 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.87A 3hcrA-4of8A:
undetectable		 3hcrA-4of8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 7 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.90A 3hcrB-4of8A:
undetectable		 3hcrB-4of8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 8 LEU A  67
PRO A  34
SER A 121
GLY A 125
 None
None
None
GOL  A 302 (-3.6A)
 0.92A 4klrB-4of8A:
undetectable		 4klrB-4of8A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 4of8 IRREGULAR CHIASM
C-ROUGHEST PROTEIN
(Drosophila
melanogaster) 		4 / 7 VAL A  45
GLN A  37
LEU A  47
SER A  91
 None
 1.05A 4zphA-4of8A:
undetectable
4zphB-4of8A:
undetectable		 4zphA-4of8A:
18.91
4zphB-4of8A:
18.66