SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ofd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4ofd KIN OF IRRE-LIKE
PROTEIN 1
(Mus
musculus) 		4 / 6 GLU A 192
ASP A 197
PHE A 202
ARG A 162
 None
 1.29A 2a3bB-4ofdA:
undetectable		 2a3bB-4ofdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 4ofd KIN OF IRRE-LIKE
PROTEIN 1
(Mus
musculus) 		3 / 3 ARG A  75
SER A  97
TYR A  76
 None
 1.04A 2q2hA-4ofdA:
undetectable
2q2hB-4ofdA:
undetectable		 2q2hA-4ofdA:
19.70
2q2hB-4ofdA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4ofd KIN OF IRRE-LIKE
PROTEIN 1
(Mus
musculus) 		3 / 3 TRP A  57
VAL A 120
ARG A 182
 None
 0.91A 3b0wA-4ofdA:
undetectable		 3b0wA-4ofdA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4ofd KIN OF IRRE-LIKE
PROTEIN 1
(Mus
musculus) 		4 / 8 TRP A  57
THR A  58
TYR A 102
ARG A 114
 None
 1.25A 5tzoB-4ofdA:
undetectable		 5tzoB-4ofdA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4ofd KIN OF IRRE-LIKE
PROTEIN 1
(Mus
musculus) 		4 / 8 TRP A  57
THR A  58
TYR A 102
ARG A 114
 None
 1.34A 5tzoC-4ofdA:
undetectable		 5tzoC-4ofdA:
21.97