SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ofn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ofn GLUTATHIONE
S-TRANSFERASE-1
(Necator
americanus) 		4 / 7 PHE A 206
PHE A 106
TYR A 107
GLY A 115
 None
 0.99A 3em0B-4ofnA:
undetectable		 3em0B-4ofnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 4ofn GLUTATHIONE
S-TRANSFERASE-1
(Necator
americanus) 		4 / 8 ILE A  11
TYR A 107
VAL A  51
ASP A  31
 None
None
GSH  A 301 (-4.5A)
None
 1.16A 5vlmF-4ofnA:
undetectable		 5vlmF-4ofnA:
24.09