SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ofs'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Y_B_MK1B524_1 (PROTEIN (PROTEASE))	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	6 / 11	ALA A 114 VAL A  67 GLY A  61 ILE A 126 THR A 149 ILE A  96	None	1.10A	1c6yA-4ofsA: undetectable	1c6yA-4ofsA: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DG5_A_TOPA201_1 (DIHYDROFOLATE REDUCTASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 11	ILE A  98 ILE A  66 SER A  69 LEU A  71 ILE A  96	None	1.17A	1dg5A-4ofsA: undetectable	1dg5A-4ofsA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWJ_B_BAXB1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	3 / 3	ILE A  66 ASP A 209 PHE A 206	None	0.66A	1uwjB-4ofsA: undetectable	1uwjB-4ofsA: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DTJ_B_THRB402_0 (ASPARTOKINASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 9	ILE A 111 ILE A 150 GLY A  61 ALA A  64 THR A 149	None	1.09A	2dtjA-4ofsA: undetectable 2dtjB-4ofsA: undetectable	2dtjA-4ofsA: 22.75 2dtjB-4ofsA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_C_VDYC6178_1 (VITAMIN D HYDROXYLASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 12	MET A  43 ILE A  46 LEU A  47 ASN A 152 ILE A  66	None	1.13A	3a51C-4ofsA: undetectable	3a51C-4ofsA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL4_A_ROCA100_2 (PROTEASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 9	ALA A 114 VAL A  67 GLY A  61 ILE A 126 THR A 149	None	1.02A	3el4B-4ofsA: undetectable	3el4B-4ofsA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FRQ_B_ERYB195_0 (REPRESSOR PROTEIN MPHR(A))	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 12	GLY A  97 LEU A 189 ILE A 122 SER A 123 VAL A 175	None	1.04A	3frqB-4ofsA: undetectable	3frqB-4ofsA: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_1 (HIV-1 PROTEASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 9	ALA A 114 VAL A  67 GLY A  61 ILE A 126 THR A 149	None	0.99A	3spkA-4ofsA: undetectable	3spkA-4ofsA: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_2 (HIV-1 PROTEASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 12	ALA A 114 VAL A  67 GLY A  61 ILE A 126 THR A 149	None	1.00A	3spkB-4ofsA: undetectable	3spkB-4ofsA: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	3 / 3	PHE A  32 CYH A 193 HIS A 195	None	1.04A	3u9fG-4ofsA: 16.6	3u9fG-4ofsA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6E_A_SAMA1349_1 (HYDROXYINDOLE O-METHYLTRANSFERASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	3 / 3	TYR A  88 ASP A 194 ASP A 199	None	0.84A	4a6eA-4ofsA: undetectable	4a6eA-4ofsA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DUB_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT 9D7)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	4 / 6	PHE A 148 ALA A 171 GLY A 174 LEU A 191	None	1.05A	4dubA-4ofsA: undetectable	4dubA-4ofsA: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ1_B_AB1B201_0 (HIV-1 PROTEASE)	4ofs	PROBABLE LIPOAMIDE ACYLTRANSFERASE (Thermoplasma acidophilum)	5 / 12	GLY A 174 VAL A  59 GLY A 157 GLY A 158 ILE A 159	None	0.78A	6dj1A-4ofsA: undetectable	6dj1A-4ofsA: 16.67