SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ogq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4ogq APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		3 / 3 GLN C 159
HIS C  26
ARG C 155
 None
HEM  C 301 (-3.7A)
None
 0.94A 1zlqA-4ogqC:
undetectable		 1zlqA-4ogqC:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 4ogq APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE C  52
ILE C 127
VAL C 101
VAL C 114
ILE C  20
 None
 0.94A 2nnhA-4ogqC:
undetectable		 2nnhA-4ogqC:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4ogq APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		4 / 6 TYR C   9
TYR C 106
GLN C 104
ILE C 115
 None
 1.21A 2pgzD-4ogqC:
2.7
2pgzE-4ogqC:
2.6		 2pgzD-4ogqC:
20.24
2pgzE-4ogqC:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4ogq APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		5 / 9 ASP C 198
VAL C 225
ALA C 224
SER C 181
GLY C 222
 None
 1.15A 4mm5A-4ogqC:
undetectable		 4mm5A-4ogqC:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 4ogq APOCYTOCHROME F
(Nostoc
sp.
PCC
7120) 		5 / 11 ASP C 198
VAL C 225
ALA C 224
SER C 181
GLY C 222
 None
 1.23A 4mmaA-4ogqC:
undetectable		 4mmaA-4ogqC:
22.07