SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ogr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_H_ACTH3006_0 (BETA-CARBONIC ANHYDRASE)	4ogr	PROTEIN TAT (Human immunodeficiency virus 1)	4 / 6	CYH D 34 VAL D 36 HIS D 33 CYH D 22	ZN D 101 (-2.4A) None ZN D 101 (-3.1A) ZN D 101 (-2.2A)	1.27A	1ekjG-4ogrD: undetectable 1ekjH-4ogrD: undetectable	1ekjG-4ogrD: 12.22 1ekjH-4ogrD: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	4ogr	PROTEIN TAT (Human immunodeficiency virus 1)	3 / 3	CYH D 31 PHE D 38 PHE D 32	None	0.76A	3cr5X-4ogrD: undetectable	3cr5X-4ogrD: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DTU_B_CUB1022_0 (CYTOCHROME C OXIDASE SUBUNIT 2)	4ogr	PROTEIN TAT (Human immunodeficiency virus 1)	3 / 3	CYH D 22 CYH D 34 HIS D 33	ZN D 101 (-2.2A) ZN D 101 (-2.4A) ZN D 101 (-3.1A)	0.86A	3dtuB-4ogrD: undetectable	3dtuB-4ogrD: 11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DTU_D_CUD3_0 (CYTOCHROME C OXIDASE SUBUNIT 2)	4ogr	PROTEIN TAT (Human immunodeficiency virus 1)	3 / 3	CYH D 22 CYH D 34 HIS D 33	ZN D 101 (-2.2A) ZN D 101 (-2.4A) ZN D 101 (-3.1A)	0.84A	3dtuD-4ogrD: undetectable	3dtuD-4ogrD: 11.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EKJ_H_ACTH3006_0","BETA-CARBONIC ANHYDRASE","4ogr","PROTEIN TAT","Human immunodeficiency virus 1",4,"CYH D  34;VAL D  36;HIS D  33;CYH D  22"," ZN D 101 (-2.4A);None; ZN D 101 (-3.1A); ZN D 101 (-2.2A)","1.27A","1ekjG-4ogrD:undetectable;1ekjH-4ogrD:undetectable","1ekjG-4ogrD:12.22;1ekjH-4ogrD:12.22"],["3CR5_X_PNTX95_0","PROTEIN S100-B","4ogr","PROTEIN TAT","Human immunodeficiency virus 1",3,"CYH D  31;PHE D  38;PHE D  32","None","0.76A","3cr5X-4ogrD:undetectable","3cr5X-4ogrD:15.15"],["3DTU_B_CUB1022_0","CYTOCHROME C OXIDASE SUBUNIT 2","4ogr","PROTEIN TAT","Human immunodeficiency virus 1",3,"CYH D  22;CYH D  34;HIS D  33"," ZN D 101 (-2.2A); ZN D 101 (-2.4A); ZN D 101 (-3.1A)","0.86A","3dtuB-4ogrD:undetectable","3dtuB-4ogrD:11.82"],["3DTU_D_CUD3_0","CYTOCHROME C OXIDASE SUBUNIT 2","4ogr","PROTEIN TAT","Human immunodeficiency virus 1",3,"CYH D  22;CYH D  34;HIS D  33"," ZN D 101 (-2.2A); ZN D 101 (-2.4A); ZN D 101 (-3.1A)","0.84A","3dtuD-4ogrD:undetectable","3dtuD-4ogrD:11.82"]]